Evidence map›Paper›PMID 40048834›Full record

ArticleClinical biomechanics (Bristol, Avon)2025

Does joint hypermobility exacerbate altered landing and jumping strategies in adolescents with fibromyalgia syndrome compared to controls?

Tessa C Hulburt, William R Black, Scott Bonnette, Staci Thomas, Andrew Schille, Chris DiCesare, Matthew S Briggs, Sylvia Ounpuu, Susmita Kashikar-Zuck, Greg D Myer

Abstract read
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Article in Clinical biomechanics (Bristol, Avon), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Tessa C HulburtEmory Sports Performance and Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Health Services Research Center, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: thulbur@emory.edu.
William R BlackDepartment of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.
Scott BonnetteDivision of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Staci ThomasDivision of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Andrew SchilleEmory Sports Performance and Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA.
Chris DiCesareExponent, Inc., Detroit, MI, USA.
Matthew S BriggsSports Medicine Research Institute, School of Health and Rehabilitation Sciences, and Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Sylvia OunpuuCenter for Motion Analysis, Connecticut Children's Medical Center, Department of Orthopedic Surgery, University of Connecticut School of Medicine, Farmington, CT, USA.
Susmita Kashikar-ZuckDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Greg D MyerEmory Sports Performance and Research Center (SPARC), Flowery Branch, GA, USA; Emory Sports Medicine Center, Atlanta, GA, USA; Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA, USA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA; Youth Physical Development Centre, Cardiff Metropolitan University, Wales, UK; The Micheli Center for Sports Injury Prevention, Waltham, MA, USA.

Funding

Multi-site Randomized Clinical Trial of FIT Teens for Juvenile FibromyalgiaR01AR070474 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI KASHIKAR-ZUCK, SUSMITA · 2017 to 2023
$8.7M
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)P30AR076316 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI DUMOULIN, CHARLES L. · 2019 to 2023
$3.4M
AHRQ HHS T32 HS029585NIAMS NIH HHS P30 AR076316NIAMS NIH HHS R01 AR070474
6 · The paper itself

Abstract

backgroundJoint hypermobility is common in children and persists in various genetic and connective tissue disorders, including conditions characterized by chronic musculoskeletal pain (i.e. Juvenile Fibromyalgia Syndrome), which involves movement dysfunction. It is unclear if joint hypermobility contributes to this dysfunction. This study investigated whether generalized joint hypermobility is associated with altered landing/jumping biomechanics in adolescents with juvenile fibromyalgia syndrome compared to controls.

methodsAdolescents with juvenile fibromyalgia syndrome and hypermobility (n = 17), juvenile fibromyalgia syndrome without hypermobility (n = 17), and non-hypermobile controls (n = 17) performed a landing/jumping task while 3D-motion capture and ground reaction force data were collected. Timewise data were compared using statistical parametric mapping.

findingsBoth groups with juvenile fibromyalgia syndrome exhibited altered lower extremity biomechanics compared to controls, including increased sagittal hip and ankle kinematics (P < 0.0001), ∼25 % reduced sagittal knee and ankle kinetics (P ≤ 0.038) and ∼ 2.5× greater knee internal rotation (P < 0.0001) during landing/jumping, as well as ∼75 % and ∼ 20 % reduced ground reaction force during initial landing and jumping (P < 0.0001), respectively. Both groups with juvenile fibromyalgia syndrome, demonstrated 17-26 % reduced landing depth (P < 0.0001;d ≤ 1.79) and 26 % reduced jump height (P ≤ 0.01;d ≤ 0.86), indicating inefficient momentum absorption.

interpretationAltered biomechanics observed in both groups with juvenile fibromyalgia syndrome may reflect an attempt to avoid pain. While hypermobility did not significantly differentiate the groups with juvenile fibromyalgia syndrome overall, it was associated with more inefficiencies. This study highlights the need for hypermobility-specific movement assessments to understand movement-associated pain, strength, and kinesthetics to improve early identification and treatment of youth with hypermobility at risk for chronic pain and functional limitations.

Indexed as

FibromyalgiaJoint InstabilityAdolescentBiomechanical PhenomenaCase-Control StudiesChildFemaleHumansKnee JointMaleMovementRange of Motion, ArticularBiomechanicsChronic painFibromyalgiaHypermobilityJumpLand

Identifiers

PMID40048834
PMCPMC11993334

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.