Evidence map›Paper›PMID 40048715›Full record

ArticleThe Journal of invasive cardiology2025

Sex differences and the role of anemia in contrast-associated acute kidney injury after percutaneous coronary intervention.

Neil Zhang, Kyla Sherwood, Brian Claggett, Sanket Dhruva, Ashishdeep Sandhu, Susan Cheng, Joseph Ebinger

Abstract read
In one paragraph

Article in The Journal of invasive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neil ZhangCedars-Sinai Medical Center, Los Angeles, California.
Kyla SherwoodDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Brian ClaggettCardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts.
Sanket DhruvaSection of Cardiology, San Francisco Veterans Affairs Medical Center, San Francisco, California.
Ashishdeep SandhuBiome Analytics, San Francisco, California.
Susan ChengCedars-Sinai Medical Center, Los Angeles, California.
Joseph EbingerCedars-Sinai Medical Center, Los Angeles, California. Email: cda-research@cshs.org.

Funding

Training in Advanced Heart Disease ResearchT32HL116273 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Joshua I Goldhaber, EDUARDO MARBAN · 2013 to 2026
$5.6M
Implementation Science to Improve Cardiovascular Health: Leveraging EHR Systems to Advance Care of Resistant HypertensionK23HL153888 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI EBINGER, JOSEPH · 2020 to 2024
$929k
NHLBI NIH HHS K23 HL153888NHLBI NIH HHS T32 HL116273
6 · The paper itself

Abstract

Many, though not all, studies suggest that contrast-associated acute kidney injury (CA-AKI) after percutaneous coronary intervention (PCI) rates are higher in women. The authors sought to clarify the presence of and factors contributing to possible sex differences. Among 2971 consecutive patients undergoing PCI, women experienced higher crude rates of CA-AKI. However, this association was significantly attenuated after adjusting for demographic and comorbid conditions, particularly pre-procedural anemia, which accounted for a substantial proportion of the excess risk. The study offers clarification regarding the higher post-PCI risks among women and underscores the role of anemia as a prevalent contributor to CA-AKI.

Indexed as

Acute Kidney InjuryAnemiaContrast MediaPercutaneous Coronary InterventionAgedCoronary AngiographyFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsSex FactorsContrast Mediacontrast-induced acute kidney injurypercutaneous coronary intervention

Identifiers

PMID40048715
PMCPMC12328099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.