ArticleJournal of veterinary internal medicine
Evaluation of an Automated Fluorescence Enzyme Immunoassay for Quantification of Equine Insulin and Comparison to Five Other Immunoassays.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prevalence of insulin dysregulation in a sport horse population as determined by traditional and stall-side testing.Equine veterinary journal · 2026Article
- The Effect of Lipemia on Insulin and Adiponectin Measurement in Equine Blood Samples.Veterinary clinical pathology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundHyperinsulinemia is an important and treatable risk factor for laminitis in horses.
objectivesEvaluate the Tosoh AIA-360 automated fluorescence enzyme immunoassay for the measurement of serum insulin concentrations in horses, and compare it to five other immunoassays for insulin quantification. ANIMALS: One hundred serum samples from 83 horses were submitted for insulin measurement.
methodsThe Tosoh AIA-360 was assessed against a reference assay (radioactive immunoassay; RIA). Using the same samples, TOS-FEIA, ELISA, and three chemiluminescent immunoassays (CLIA) were assessed for correlation and agreement with RIA.
resultsThe TOS-FEIA showed excellent correlation with RIA (r CONCLUSIONS AND CLINICAL IMPORTANCE: The TOS-FEIA had acceptable accuracy and precision for clinical use, including at concentrations of insulin < 100 μIU/mL. The ELISA and one CLIA (Cobas e) showed acceptable accuracy, but the Cobas e demonstrated marked bias compared with RIA. Both Immulite CLIA assays exhibited unacceptable accuracy.
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Registered trials
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