Evidence map›Paper›PMID 40048454›Full record

Trial reportPLoS medicine2025

Effects of a community-driven water, sanitation, and hygiene intervention on diarrhea, child growth, and local institutions: A cluster-randomized controlled trial in rural Democratic Republic of Congo.

John P Quattrochi, Kevin Croke, Caleb Dohou, Luca Stanus Ghib, Yannick Lokaya, Aidan Coville, Eric Mvukiyehe

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PLoS medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Sociodemographic Factors and Childhood Growth: Associations with Environmental Sanitation Phases.International journal of environmental research and public health · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

John P QuattrochiDepartment of Global Health, School of Health, Georgetown University, Washington, DC, United States of America.ORCID https://orcid.org/0000-0003-0591-5931
Kevin CrokeDepartment of Global Health & Population, Harvard TH Chan School of Public Health, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-4750-9280
Caleb DohouWorld Bank Country Office, Kinshasa, Democratic Republic of Congo.
Luca Stanus GhibDevelopment Impact (DIME) Department, World Bank, Washington, DC, United States of America.
Yannick LokayaWorld Bank Country Office, Kinshasa, Democratic Republic of Congo.
Aidan CovilleDevelopment Impact (DIME) Department, World Bank, Washington, DC, United States of America.ORCID https://orcid.org/0000-0002-3437-6239
Eric MvukiyeheDepartment of Political Science, Duke University, Durham, North Carolina, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiarrhea and growth faltering in early childhood reduce survival and impair neurodevelopment. We assessed whether a national program combining (i) funds for latrine and water upgrades; (ii) institutional strengthening; and (iii) behavior change campaigns reduced diarrhea and stunting, and strengthened local institutions. METHODS AND

findingsWe collaborated with program implementers to conduct a cluster-randomized controlled trial in four provinces of the Democratic Republic of Congo (DRC). Three hundred thirty-two rural villages were grouped into 121 clusters to minimize geographic spillovers. Between 15 March and 30 June 2018, we randomly assigned, after stratifying by province and cluster size, 50 intervention and 71 control clusters. Masking of participants and interviewers was not possible. Primary outcomes were length-for-age Z-score among children under 5 years of age, caregiver-reported diarrhea in last 7 days among children under 5 years of age, and an index of community WASH institutions. The primary analysis was on an intention-to-treat basis, using a binary variable indicating whether the participant was in an intervention or control cluster. Three thousand two hundred eighty-three households were interviewed between November 2022 and April 2023, median 3.6 years post-intervention. The intervention had no effect on diarrhea (adjusted mean difference -0.01 [95% -0.05 to 0.03]). Diarrhea prevalence was high overall, at 38% in the treatment group and 42% in the control group. The intervention had no effect on length-for-age Z-scores in children (adjusted mean difference -0.01 [95% CI -0.15 to 0.12]). In the control group, the mean length-for-age Z-score was -2.18 (1.60 SD). Villages in the intervention group had a 0.40 higher score on the WASH institutions index (95% CI 0.16-0.65). The percentage of villages in the intervention group with an active water, sanitation, and hygiene (or just water) committee was 21 pp higher than the control group. Households in the intervention group were 24 pp (95% CI 12-36) more likely to report using an improved water source, 18 pp (95% CI 10-25) more likely to report using an improved sanitation facility, and reported more positive perceptions of water governance (adjusted difference 0.19 SD [95% CI 0.04-0.34]). The trial had several limitations, including incomplete (86%) adherence in the implementation group, the absence of baseline measures, and the reliance on self-reported outcomes for some measures.

conclusionsThe DRC's national rural WASH program increased access to improved water and sanitation infrastructure, and created new WASH institutions, all of which persisted for at least 3.6 years. However, these effects were not sufficient to reduce diarrhea or growth faltering.

trial registrationThe Pan African Clinical Trials Registry PACTR202102616421588 (https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=14670). The American Economics Association RCT registry AEARCTR-0004648 (https://www.socialscienceregistry.org/trials/4648).

Indexed as

Child DevelopmentDiarrheaGrowth DisordersHygieneSanitationWater SupplyChild, PreschoolDemocratic Republic of the CongoFemaleHumansInfantMaleRural Population

Identifiers

PMID40048454
PMCPMC11884671

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.