Evidence map›Paper›PMID 40048426›Full record

ArticleThe Journal of frailty & aging2025

Frailty and associated healthcare expenditures among patients undergoing total hip and knee arthroplasty.

Donna Ron, Alton B Daley, Marcus P Coe, Michael D Herrick, Robert H Roth, Alexander T Abess, Pablo Martinez-Camblor, Stacie G Deiner, Myles D Boone

Abstract read
In one paragraph

Article in The Journal of frailty & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Donna RonDepartment of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH; Department of Anesthesiology, Critical Care, and Pain Medicine, Meir Medical Center and Tel Aviv University, 59 Tchernichovsky St, Kefar Sava 4428164, Israel. Electronic address: Donna.Ron@clalit.org.il.
Alton B DaleyDepartment of Orthopaedic Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Marcus P CoeDepartment of Orthopaedic Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Michael D HerrickDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Robert H RothDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Alexander T AbessDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Pablo Martinez-CamblorDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH.
Stacie G DeinerDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.
Myles D BooneDepartment of Anesthesiology and Perioperative Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH; Department of Neurology, Dartmouth Hitchcock Medical Center, Lebanon, NH, Geisel School of Medicine at Dartmouth, Hanover, NH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor joint surgery is one of the largest components of Medicare spending in the US and the most frequent major procedure performed in older adults. Increasing age is associated with increasing prevalence of frailty, but the influence of frailty on healthcare expenditures following arthroplasty has yet to be adequately explored.

objectiveTo explore the association between frailty and healthcare expenditures in the year following total hip and knee arthroplasties.

designRetrospective cohort study

settingUnited States population

participantsMedicare beneficiaries 65 and older undergoing total knee or hip arthroplasty (n = 1,152,872) from 2017 through 2018. MEASUREMENTS: Claims-based frailty index (exposure), total 1-year Medicare expenditures broken down by category (primary outcome), in-hospital complications, length of stay, discharge destination, readmission and mortality (secondary outcomes).

resultsAmong 435,496 patients who underwent hip (37.8 %) and 717,376 patients who underwent knee arthroplasty (62.2 %), the mean age was 73.7 years and 19.2 % were classified as frail. Median total expenditures in US dollars at one year were higher in those with frailty ($247,503; IQR [$169,400-$391,176]) relative to the prefrail ($179,379 [$127,396-$265,039]) and robust ($130,314 [$85,438-$199,605]) groups. Total expenditures included the index surgical admission, rehospitalization, skilled nursing care, and outpatient care, all of which were higher with increasing frailty. However, the surgical procedure accounted for less than a third of the total 1-year healthcare costs and was the category with the lowest degree of variation between patients. Frailty was also associated with longer lengths of stay, higher risks of complications, readmission, and mortality and lower likelihood of being discharged home after the procedure.

conclusionsAmong older adults undergoing total hip and knee arthroplasty, frailty is associated with higher healthcare expenditures, predominantly driven by longitudinal care during the year following the procedure. More research is needed to test interventions to improve outcomes and reduce cost in this high-risk population.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeFrail ElderlyFrailtyHealth ExpendituresAgedAged, 80 and overFemaleHumansLength of StayMaleMedicarePostoperative ComplicationsRetrospective StudiesUnited StatesArthroplastyFrailtyHealth expendituresMedicare

Identifiers

PMID40048426
PMCPMC12184003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.