Evidence map›Paper›PMID 40048272›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Meiqi Lin, Zeling Du, Dan Guo, Yiran Zhang, Jiameng Dan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meiqi LinState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.ORCID 0009-0007-5828-9360
Zeling DuState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.
Dan GuoState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.ORCID 0009-0005-5820-4860
Yiran ZhangState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.
Jiameng DanState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.ORCID 0009-0009-9178-881X

Funding

MOST | National Natural Science Foundation of China (NSFC) 32270845| Natural Science Foundation of Yunnan Province (Yunnan Natural Science Foundation) 202102AA100053Xingdian Talent Support Program of Yunnan Province KKRD202273103Yunnan Fundamental Research Projects 202201BE070001-006Yunnan Fundamental Research Projects 202301AT070304
6 · The paper itself

Abstract

Zygotic genome activation (ZGA) confers to the mouse two-cell (2C) embryo a unique transcriptional profile characterized by transient up-regulation of many totipotency-related genes and

Indexed as

Gene DuplicationGene Expression Regulation, DevelopmentalHomeodomain ProteinsMultigene FamilyAnimalsDNA MethylationEmbryonic DevelopmentMiceMouse Embryonic Stem CellsZygoteHomeodomain Proteins2C-like stateDux cluster duplicationtotipotencyzygotic genome activation

Identifiers

PMID40048272
PMCPMC11912362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.