ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025
Ratiometric electrochemical aptasensor based on functionalized graphene nanocomposites for detection of CA19-9.
Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Aptamer-Based Strategies for Colorectal Cancer Detection: Emerging Technologies and Future Directions.Biosensors · 2025Review
- Early-Stage Pancreatic Cancer Diagnosis: Serum Biomarkers and the Potential for Aptamer-Based Biosensors.Molecules (Basel, Switzerland) · 2025Review
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Authors and funding
8 authors.
Funding
Abstract
A ratiometric electrochemical aptasensor was constructed based on rGO-cMWCNTs/AuNPs functionalized graphene nanocomposites for the detection of CA19-9 in serum samples. First, rGO-cMWCNTs/AuNPs nanocomposites were modified on the surface of glassy carbon electrodes. Second, the aptamer complementary chain labeled with anthraquinone-2-carboxylic acid (cDNA-AQ) was covalently linked by Au-S. Finally, the hybrid chain was formed with ferrocene (Fc)-labeled Apt-Fc by base pairing, and a sensing interface with specific target recognition and electrochemical signal amplification was constructed. In this study, the ratio of response signal to internal reference signal (I
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Registered trials
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