Evidence map›Paper›PMID 40048032›Full record

ArticleActa neurochirurgica2025

B-waves in noninvasive capacitance signal correlate with B-waves in ICP.

Andreas Spiegelberg, Andrea Boraschi, Ramy Amirah, Katharina Wolf, Mukesch Shah, Laura Krismer, Jürgen Beck, Vartan Kurtcuoglu

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In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Andreas SpiegelbergThe Interface Group, Department of Physiology, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
Andrea BoraschiThe Interface Group, Department of Physiology, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.
Ramy AmirahDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.
Katharina WolfDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.
Mukesch ShahDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.
Laura KrismerDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.
Jürgen BeckDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.
Vartan KurtcuogluThe Interface Group, Department of Physiology, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. vartan.kurtcuoglu@uzh.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnalysis of B-waves in overnight intracranial pressure (ICP) recordings used to be an important element in the diagnosis of normal pressure hydrocephalus (NPH). Here, we tested the hypothesis that equivalents to B-waves can be detected and quantified in a noninvasively measured electric capacitance signal termed W.

methodsWe measured ICP and W in a cohort of 15 patients with suspected diagnosis of NPH or spontaneous intracranial hypotension during infusion testing, identifying B-waves in both signals by wave-template matching in the time domain.

resultsWe found very strong correlation between the duration of B-waves in ICP and W (R

conclusionsThe concurrent presence of B-waves in the signals suggests that vasogenic activity of cerebral autoregulation is reflected in W. The weaker correlation of amplitudes may be attributed to W being an indirect measure of cranial volume composition, whereas ICP is a measure of pressure, with the two linked by the non-linear craniospinal pressure-volume relation that varies between patients. Analysis of the noninvasively acquired W signal should be evaluated as a triage tool for patients with NPH and other disorders characterized by reduced compliance.

Indexed as

Hydrocephalus, Normal PressureIntracranial PressureAdultAgedAged, 80 and overElectric CapacitanceFemaleHumansMaleMiddle AgedB-wavesCraniospinal complianceIntracranial pressureNoninvasive measurementNormal pressure hydrocephalusSlow vasogenic waves

Identifiers

PMID40048032
PMCPMC11885407

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.