Evidence map›Paper›PMID 40047970›Full record

ReviewTropical animal health and production2025

Genomic selection, gene editing, and reproductive biotechnology: a triad for the improvement of native buffalo breeds in a developing country perspective like Pakistan.

Raja Danish Muner, Muhammad Moaeen-Ud-Din, Ali Haider Saleem, Qudrat Ullah, Ghulam Abbas, Babar Maqbool, Masroor Ellahi Babar, Yanzhen Bi, Farhan Farooq

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Review in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raja Danish Muner *Department of Animal Breeding & Genetics, The University of Agriculture, Dera Ismail Khan, Pakistan. danishmunirraja@gmail.com.ORCID http://orcid.org/0009-0003-8270-1109
Muhammad Moaeen-Ud-Din *Department of Animal Breeding & Genetics, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Ali Haider SaleemDepartment of Animal Sciences, College of Veterinary and Animal Sciences, Jhang, Pakistan.
Qudrat UllahDepartment of Theriogenology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Ghulam AbbasDepartment of Biotechnology, The University of Agriculture, Dera Ismail Khan, Pakistan.
Babar MaqboolDepartment of Veterinary Medicine, The University of Agriculture, Dera Ismail Khan, Pakistan.
Masroor Ellahi BabarDepartment of Animal Breeding & Genetics, The University of Agriculture, Dera Ismail Khan, Pakistan.
Yanzhen BiKey Laboratory of Animal Embryo Engineering and Molecular Breeding of Hubei Province, Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Farhan FarooqDepartment of Poultry Science, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pakistan is the 2nd largest country in buffalo population in the world. The current population of buffalo in Pakistan is 45.0 million heads whereas the current world buffalo population is 200 million heads. Pakistan is home to one of the best buffalo breeds in the world i.e., Nili, Ravi, Nili-Ravi, Kundi, and Azi Khaili. Moreover, Pakistan is ranked 2nd largest buffalo-milk-producing country in the world. Keeping in consideration, the tremendous role and importance of buffalo, the current study aims to provide a comprehensive overview of the important genetic studies conducted up till now and the need to apply the latest genomic tools, gene editing, and reproductive biotechnologies for the improvement of these native buffalo breeds. The current research is limited to a few diversity studies, basic phylogenetics, evolution, and genetic characterization using only a few loci and phenotypic studies of limited productive traits. The current picture is gloomy as proper genetic characterization and diversity study of these breeds has never been made using reliable, accurate, and advanced genomic techniques. In a developing country like Pakistan where there is no comprehensive data collection coupled with scattered farming without any organized breeding system; genomic selection, gene editing, and application of advanced reproductive biotechnology techniques are the most promising techniques for rapid and sustainable development in the productive and reproductive potential of our Black Gold. Advancement in the methods of genotyping using commercially available SNP Chips at affordable prices along with improvements in reproductive biotechnology and genome editing techniques will provide the framework for the true genetic exploration and optimal utilization of precious native buffalo breeds potential. Conclusively, these techniques have great potential to revolutionize the world's buffalo population.

Indexed as

BiotechnologyBreedingBuffaloesGene EditingSelection, GeneticAnimalsDeveloping CountriesGenomicsPakistanBuffaloGene EditingGenomic SelectionReproductive BiotechnologySNP Chip

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.