ArticleFish physiology and biochemistry2025
Hypoxia tolerance and physiological coping strategies in fat greenling (Hexagrammos otakii).
Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Dissolved oxygen (DO) is necessary for fish survival and growth. This study investigated the hypoxia tolerance, hematological indexes, hepatic antioxidant capacity, and liver and gill morphological alternation of fat greenling during hypoxia stress. Changes in hematological parameters (cortisol, glucose, lactic acid, hemoglobin [Hb], hematocrit [Hct], and white blood cell [WBC], and red blood cell [RBC] numbers), hepatic antioxidant enzymes (superoxide dismutase [SOD], glutathione peroxidase [GSH-Px], catalase [CAT]), aminotransferase (AST), alanine aminotransferase (ALT) activities, and malondialdehyde (MDA) contents, and the histology of the liver and gill were evaluated under hypoxia stress and reoxygenation. Results showed that the DO at critical oxygen tension (Pcrit) and loss of equilibrium (LOE) were 3.10 ± 0.17 mg/L and 1.90 ± 0.11 mg/L, respectively. Hypoxia stress significantly stimulated the respiratory frequency rate, Hb and Hct levels, and RBC numbers; the highest values were observed at Pcrit and LOE, respectively. Serum glucose, cortisol and lactic acid contents, and hepatic MDA, AST, ALT, SOD, and CAT activity demonstrated similar results to Hb. However, hepatic GSH-Px activity obtained the highest value at Pcrit and drastically decreased the lowest value at LOE. Moreover, hypoxia stress induced hepatocyte necrosis, vacuolization, and increased hepatocyte apoptosis rate. Lamellar perimeters, length, surface area, and gill surface area manifested results similar to those for respiratory frequency rate, whereas lamellar width and interlamellar distance significantly decreased at Pcrit, LOE, and reoxygenation treatment for 4 h. The above parameters returned to nearly normal levels after reoxygenation treatment for 8 h. These results suggest that fat greenling is a hypoxia-tolerant marine fish that copes with potential hypoxia-induced damage by elevating hematological-related parameters, stimulating hepatic antioxidant capacity, and altering the gill and liver morphology to maintain homeostasis.
Indexed as
Identifiers
40047949What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.