Trial reportClinical oral investigations2025
Whitening efficacy and removal of extrinsic tooth stain of sodium phytate-containing whitening toothpaste: a randomized controlled trial.
Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Silica-Based Abrasive Ingredients on Fluoride Concentration in Toothpaste: An In Vitro and In Vivo Study.Dentistry journal · 2026Article
- Clinical myths in dental bleaching: an evidence-based structured narrative review.Brazilian oral research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study aimed to evaluate the whitening efficacy and removal of extrinsic tooth stain of sodium phytate-containing whitening toothpaste, as well as to evaluate participant satisfaction.
methodsA total of eighty participants were recruited for this randomized, triple-blind controlled trial and were randomly assigned to either the test group (toothpaste containing 0.875% sodium phytate, ST) or the control group (toothpaste without sodium phytate, CT). Tooth color was assessed using a VITA spectrophotometer and changes in exogenous tooth stains were evaluated using the Lobene Index, which were conducted at baseline, as well as at 2, 3, and 4 weeks. Additionally, participants' self-assessment of tooth color were evaluated through an aesthetic numerical analogue scale. Statistical tests were conducted appropriately, and the significance level was established at α = 0.05.
resultsThis study demonstrates that the b-value of the index teeth in the ST group was significantly lower (p < 0.05) than that of the CT group, while the △WI
conclusionBrushing teeth with sodium phytate-containing whitening toothpaste for a duration of three weeks demonstrates notable whitening effects, which significantly increase over time. However, after four weeks, the sodium phytate-containing toothpaste shows minimal efficacy in removing extrinsic tooth stains. CLINICAL SIGNIFICANCE: Sodium phytate may be incorporated into toothpaste as a whitening agent.
Indexed as
Identifiers
40047933What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.