Evidence map›Paper›PMID 40047865›Full record

SynthesisSurgical endoscopy2025

Radioactive stent versus normal stent insertion for inoperable malignant biliary obstruction: a systematic review and meta-analysis.

Xiang Chen, Jiaxing Li, Wenwu Wan, Hao Zhang, Ding Xiong

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiang Chen *Department of Hepatobiliary and Pancreatic Surgery, Meishan City People's Hospital, 288, South fourth Section, dongpo avenue, Meishan, 620000, Sichuan, China.
Jiaxing Li *Department of General Surgery, Shigao Street Community Health Center, No. 1 Weishan Street, Ren Shou County, Meishan, Sichuan, China.
Wenwu WanDepartment of Hepatobiliary and Pancreatic Surgery, Meishan City People's Hospital, 288, South fourth Section, dongpo avenue, Meishan, 620000, Sichuan, China.
Hao ZhangDepartment of Hepatobiliary and Pancreatic Surgery, Meishan City People's Hospital, 288, South fourth Section, dongpo avenue, Meishan, 620000, Sichuan, China.
Ding XiongDepartment of Hepatobiliary and Pancreatic Surgery, Meishan City People's Hospital, 288, South fourth Section, dongpo avenue, Meishan, 620000, Sichuan, China. 744030940@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis examined the comparative efficacy and safety of radioactive stents versus normal metal stents for the management of malignant biliary obstruction (MBO).

methodsA comprehensive search of databases including PubMed, the Cochrane Library, and Embase was conducted to identify pertinent studies up to June 2024. The primary focus of this meta-analysis is on stent patency, postoperative survival, and the incidence of complications.

resultsThe meta-analysis revealed that there was no statistically significant difference in the occurrence of complications, such as bleeding (p = 0.32), cholangitis (P = 0.19), pancreatitis (P = 0.43), and cholecystitis (P = 0.99), between the two types of stents. However, the radioactive stent demonstrated a significant improvement in both stent patency time (HR = 0.60, 95% CI 0.50-0.73; P < 0.001) and patient survival time (HR = 0.63, 95% CI 0.53-0.74, P < 0.001).

conclusionThe results indicate that radioactive stents could present a more effective option compared to traditional stents for palliative management of malignant biliary obstruction, resulting in prolonged stent patency and potentially enhancing survival rates.

Indexed as

Bile Duct NeoplasmsCholestasisPalliative CareStentsHumansPostoperative ComplicationsTreatment Outcome125I seedMalignant biliary obstructionMeta-analysisRadioactive stentStent

Identifiers

PMID40047865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.