Evidence map›Paper›PMID 40047826›Full record

ReviewJournal of ophthalmic inflammation and infection2025

Inadequacies in uveitis: misnomers, incongruencies, persistence of obsolete terminologies & inappropriate guidelines, treatment inadequacies, and misinterpretations.

Carl P Herbort, Ioannis Papasavvas, Masaru Takeuchi, Yoshihiko Usui, De-Kuang Hwang, Sagnik Sen

Abstract readReview
In one paragraph

Review in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carl P HerbortInflammatory and Retinal Eye Diseases, Centre for Ophthalmic Specialised Care (COS), 6 Rue Charles-Monnard, Lausanne, 1003, Switzerland. cph@herbortuveitis.ch.
Ioannis PapasavvasInflammatory and Retinal Eye Diseases, Centre for Ophthalmic Specialised Care (COS), 6 Rue Charles-Monnard, Lausanne, 1003, Switzerland.
Masaru TakeuchiDepartment of Ophthalmology, National Defence Medical College, Tokorozawa, Saitama, Japan.
Yoshihiko UsuiDepartment of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
De-Kuang HwangDepartment of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan & School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Sagnik SenMedical Retina and Uveitis, Moorfields Eye Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequacies in medicine are manifold including inadequate influence of opinion leaders and consensus groups on terminology, diagnostic criteria and treatment guidelines, obsolete classifications and terms as well as misinterpretations of disease mechanisms. This is no different for uveitis and possibly even more pronounced as these are rare entities. PURPOSE: To underline inadequacies in uveitis including inadequate diagnostic criteria and treatment guidelines, misnomers, obsolescence of terminology, misinterpretation of disease processes and inadequate or underuse of investigative modalities in uveitis. This is a first report to be followed by others.

methodsA critical retrospective literature review of selected inadequacies in uveitis practice.

resultsWe investigate the mechanism of abuse of power of opinion leaders through the historical events such as the delay in acceptance of antiviral treatment for zoster ophthalmicus, report inadequacies and misnomers resulting from opinion articles or opinion surveys, inadequate treatment guidelines such as for Vogt-Koyanagi-Harada disease (VKH) , delays in adopting appropriate classifications, inappropriate pathophysiological interpretations such as for multiple evanescent white dot syndromes (MEWDS), reluctance to implement ICGA use, a crucial biomarker for choroiditis, among others.

conclusionInadequacies in uveitis are not so rare and often result from inadequate influence of opinion leaders oe groups. Some are harmless although annoying, such as misnomers, while others can be harmful such as inadequate treatment guidelines.

Identifiers

PMID40047826
PMCPMC11885766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.