Evidence map›Paper›PMID 40047624›Full record

ReviewMicromachines2025

Electrochemical and Optical Carbon Dots and Glassy Carbon Biosensors: A Review on Their Development and Applications in Early Cancer Detection.

Juana G López, Mariana Muñoz, Valentina Arias, Valentina García, Paulo C Calvo, Alejandro O Ondo-Méndez, Diana C Rodríguez-Burbano, Faruk Fonthal

Abstract readReview
In one paragraph

Review in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juana G LópezBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.
Mariana MuñozBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.ORCID 0009-0007-1249-684X
Valentina AriasBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.
Valentina GarcíaBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.ORCID 0009-0005-2161-3935
Paulo C CalvoBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.ORCID 0000-0001-5353-6368
Alejandro O Ondo-MéndezClinical Investigation Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.ORCID 0000-0003-2473-8790
Diana C Rodríguez-BurbanoGivia Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.ORCID 0000-0001-8732-6326
Faruk FonthalBiomedical Engineering Research Group-GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia.ORCID 0000-0002-9331-0491

Funding

Universidad Autónoma de Colombia project No. 22INTER-453 for the Universidad Autónoma de Occidente and the Universidad del Rosario.Universidad del Rosario project No. 22INTER-453 for the Universidad Autónoma de Occidente and the Universidad del Rosario.
6 · The paper itself

Abstract

Cancer remains one of the leading causes of mortality worldwide, making early detection a critical factor in improving patient outcomes and survival rates. Developing advanced biosensors is essential for achieving early detection and accurate cancer diagnosis. This review offers a comprehensive overview of the development and application of carbon dots (CDs) and glassy carbon (GC) biosensors for early cancer detection. It covers the synthesis of CDs and GC, electrode fabrication methods, and electrochemical and optical transduction principles. This review explores various biosensors, including enzymatic and non-enzymatic, and discusses key biomarkers relevant to cancer detection. It also examines characterization techniques for electrochemical and optical biosensors, such as electrochemical impedance spectroscopy, cyclic voltammetry, UV-VIS, and confocal microscopy. The findings highlight the advancements in biosensor performance, emphasizing improvements in sensitivity, selectivity, and stability, as well as underscoring the potential of integrating different transduction methods and characterization approaches to enhance early cancer detection.

Indexed as

biosensorscancercarbon dotselectrochemical biosensorglassy carbonoptical biosensor

Identifiers

PMID40047624
PMCPMC11857277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.