Evidence map›Paper›PMID 40047553›Full record

ArticleGlobal public health2025

From policy to practice: syndemic and intersectional challenges to ART adherence for transgender women under India's post-test and treat policy.

William Lodge, Jatin Chaudary, Shruta Rawat, Madina Agénor, Alpana Dange, Vivek R Anand, Don Operario, Matthew J Mimiaga, Katie B Biello

Abstract read
In one paragraph

Article in Global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

William LodgeJeb E. Brooks School of Public Policy, Cornell University, Ithaca, NY, USA.ORCID 0000-0001-7058-2710
Jatin ChaudaryThe Humsafar Trust, Mumbai, Maharashtra, India.
Shruta RawatThe Humsafar Trust, Mumbai, Maharashtra, India.
Madina AgénorDepartment of Behavioral and Social Health Sciences, Brown University School of Public Health, Providence, RI, USA.
Alpana DangeThe Humsafar Trust, Mumbai, Maharashtra, India.
Vivek R AnandThe Humsafar Trust, Mumbai, Maharashtra, India.
Don OperarioDepartment of Behavioral and Social Health Sciences, Brown University School of Public Health, Providence, RI, USA.
Matthew J MimiagaDepartment of Behavioral and Social Health Sciences, Brown University School of Public Health, Providence, RI, USA.
Katie B BielloDepartment of Behavioral and Social Health Sciences, Brown University School of Public Health, Providence, RI, USA.

Funding

Co-occurring factors that heighten transgender women's vulnerability to suboptimal ART adherence in IndiaR36DA056284 · NIDA · BROWN UNIVERSITY · PI LODGE, WILLIAM · 2022 to 2023
$107k
NIDA NIH HHS R36 DA056284
6 · The paper itself

Abstract

Transgender women (TGW) in India face one of the highest HIV prevalence rates among key populations in India, yet data on their engagement in the HIV care cascade is limited. This study investigates barriers and supportive factors for adhering to antiretroviral therapy (ART), which is vital for achieving viral suppression, reducing transmission risk to nearly zero (i.e. undetectable = utransmittable; U = U), and enhancing the quality of life for TGW living with HIV. Between July and September 2023, trained community recruiters recruited 30 TGW living with HIV in Mumbai and New Delhi, India. Using intersectionality and syndemic theory as guiding frameworks, we purposively sampled and conducted semi-structured qualitative interviews. The interviews revealed four main themes - two barriers and two supportive factors influencing ART adherence: the impact of poverty on syndemic factors, intersectional stigma and discrimination, empowerment to overcome barriers, and the influence of inclusive government programmes and policies in improving TGW's access to ART. Despite the availability of free ART immediately after diagnosis under India's 'test and treat' policy, economic instability and intersecting stigma hinder adherence. Our findings reveal that holistic interventions focusing on economic support, stigma reduction, and personal and collective empowerment might improve ART adherence among TGW in India.

Indexed as

Anti-Retroviral AgentsHealth PolicyHIV InfectionsMedication AdherenceSyndemicTransgender PersonsAdultFemaleHumansIndiaInterviews as TopicMaleMiddle AgedQualitative ResearchSocial StigmaAnti-Retroviral AgentsIndiaintersectionalityPeople living with HIVSDG 10: reduced inequalitiesSDG 3: good health and well-beingSDG 5: gender equalitysyndemicstransgender women

Identifiers

PMID40047553
PMCPMC12266041

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.