Evidence map›Paper›PMID 40047444›Full record

ArticleMicrobiology spectrum2025

Rapid detection of β-lactamase activity using the rapid Amp NP test.

Patrice Nordmann, Nicolas Helsens, Nicolas Kieffer, Camille Tinguely, Gilbert Greub, Laurent Poirel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrice NordmannEuropean Institute for Emerging Antibiotic Resistance, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0002-1343-1622
Nicolas HelsensEuropean Institute for Emerging Antibiotic Resistance, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0001-8902-0486
Nicolas KiefferMedical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Camille TinguelyMedical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Gilbert GreubInstitute for Microbiology, University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-9529-3317
Laurent PoirelEuropean Institute for Emerging Antibiotic Resistance, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0001-5160-5286

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infections (UTIs) are the most common bacterial infections in humans. They are mainly caused by IMPORTANCE: This work reports on a totally novel diagnostic technique, the Rapid Amp NP test for the identification of amoxicillin/ampicillin resistance in bacteria that are sources of non-complicated urinary tract infections. Those preliminary results obtained with cultured bacteria are promising. We believe its future use may contribute to reconsider aminopenicillins as a first line therapy for treating UTI infections. The corresponding patent of this test obtained both for the United States and Europe may contribute to its further industrialization.

Indexed as

beta-LactamasesGram-Negative BacteriaAnti-Bacterial AgentsBacterial Proteinsbeta-Lactam ResistanceCephalosporinsEscherichia coliGram-Positive BacteriaHumansMicrobial Sensitivity TestsUrinary Tract InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCephalosporinsnitrocefinGram negativerapid diagnostic testUTIβ-lactamase

Identifiers

PMID40047444
PMCPMC11960058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.