Evidence map›Paper›PMID 40047391›Full record

ArticleJournal of veterinary internal medicine

The Acute Patient Physiologic and Laboratory Evaluation Score and Other Prognostic Factors in Dogs With Diabetic Ketoacidosis.

Sarah M Edwards, Rebecka S Hess

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah M EdwardsDepartment of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Rebecka S HessDepartment of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3134-1348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute patient physiologic and laboratory evaluation (APPLE) scores have not been reported in dogs with diabetic ketoacidosis (DKA). HYPOTHESIS: The APPLE scores will be higher in non-survivors compared with survivors, and higher scores will predict increased mortality in dogs with DKA. ANIMALS: Eighty-five dogs with DKA; 58 survivors (68%) and 27 non-survivors (32%).

methodsRetrospective study. The APPLE scores were entered into a multivariate logistic regression model for mortality prediction. Variables related to DKA diagnosis also were examined as mortality predictors. If variables predicted mortality, an empirical optimal cut point, corresponding area under the receiver operating curve (AUC), and sensitivity and specificity for predicting mortality were calculated.

resultsMean 10-variable APPLE CONCLUSIONS AND CLINICAL IMPORTANCE: The APPLE

Indexed as

Diabetic KetoacidosisDog DiseasesAnimalsDogsFemaleMalePrognosisRetrospective StudiesSensitivity and SpecificityAPPLE scorebeta‐hydroxybutyratediabetes mellitusmortalityrisksurvival

Identifiers

PMID40047391
PMCPMC11883815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.