Trial reportCroatian medical journal2025
Evaluating oxygen reserve index-guided oxygenation for the prevention of postoperative delirium in elderly patients: a randomized controlled trial.
Trial report in Croatian medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical applications and potential use of the oxygen reserve index during the perioperative period.Korean journal of anesthesiology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the effect of oxygen reserve index (ORi)-guided titration of fraction of inspired oxygen (FiO2) on the incidence of postoperative delirium (POD) and the frequency of hyperoxemia episodes, assuming a potential link between hyperoxemia and POD.
methodsThis randomized controlled trial included 114 patients aged 65 years and older, scheduled for elective surgeries lasting over two hours at Health Sciences University Tepecik Training and Research Hospital between October 1, 2023, and July 7, 2024. Patients were randomized into the control group (n=57) or the ORi+pulse oximetry (SpO2) group (n=57). In the ORi+SpO2 group, we dynamically adjusted FiO2 based on the real-time ORi and SpO2 values, targeting 95%<SpO2≤98% and ORi 0.00. In the control group, FiO2 adjustments were guided solely by SpO2 readings, with ORi values recorded but not used for decision-making. POD was assessed with the Confusion Assessment Method (CAM) and CAM-ICU at multiple time points over 48 hours.
resultsThe incidence of POD was significantly higher in the control group than in the ORi+SpO2 group (42.1% vs 12.3%, P<0.001). The average FiO2 levels in the ORi+SpO2 group were significantly lower throughout surgery (P<0.001). The ORi+SpO2 group also exhibited a lower frequency of hyperoxemia episodes.
conclusionThe ORi-guided oxygenation strategy significantly reduced the incidence of POD in elderly patients by effectively minimizing intraoperative hyperoxemia. Optimizing intraoperative oxygenation through non-invasive monitoring may enhance perioperative outcomes.
Indexed as
Identifiers
40047161PMC11947977What OpenQuestion holds
Registered trials
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