Evidence map›Paper›PMID 40047118›Full record

ArticleAmerican journal of physiology. Cell physiology2025

Cellular and molecular contractile function in aged human skeletal muscle is altered by phosphate and acidosis and partially reversed with an ATP analog.

Aurora D Foster, Chad R Straight, Philip C Woods, Christopher Lee, Jane A Kent, Stuart R Chipkin, Edward P Debold, Mark S Miller

Erratum issuedAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Effects of acidosis and inorganic phosphate on CaAmerican journal of physiology. Cell physiology · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Aurora D FosterDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.
Chad R StraightDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.ORCID 0009-0009-7558-2205
Philip C WoodsDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.
Christopher LeeDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.ORCID 0000-0002-1317-5622
Jane A KentDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.ORCID 0000-0001-5487-2849
Stuart R ChipkinDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.
Edward P DeboldDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.ORCID 0000-0003-4936-9047
Mark S MillerDepartment of Kinesiology, University of Massachusetts, Amherst, Massachusetts, United States.ORCID 0000-0001-8309-8258

Funding

TRAINING PROGRAM IN MUSCLE RESEARCHT32AR007612 · NIAMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JAMES M ERVASTI, DAWN A LOWE · 2001 to 2026
$11.3M
Sex-specific adaptation to different resistance exercise programs in older adultsR01AG047245 · NIA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MILLER, MARK STUART · 2017 to 2021
$2.4M
HHS | NIH | National Institute on Aging (NIA) AG-047245NIAMS NIH HHS T32 AR007612NIA NIH HHS R01 AG047245
6 · The paper itself

Abstract

Skeletal muscle fatigue occurs, in part, from the accumulation of hydrogen (H

Indexed as

AcidosisAgingMuscle FatigueMuscle, SkeletalAgedDeoxyadenine NucleotidesElasticityFemaleHumansMaleMuscle Fibers, SkeletalMyosin Heavy ChainsPhosphatesViscosityDeoxyadenine NucleotidesMyosin Heavy ChainsPhosphatesagingdATPfatiguefibermyosin heavy chain

Identifiers

PMID40047118
PMCPMC12225719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.