ArticleLaryngoscope investigative otolaryngology2025
From Profiles to Structure in Cochlear Nerve: A Clinical Study of Auditory Neuropathy.
Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To investigate the clinical and audiological features in auditory neuropathy (AN) patients with different image performance of cochlear nerve (CN) on MRI. Methods: AN patients were selected from the Multicenter Study on Clinical Diagnosis and Intervention of AN (2003-2023). Subjects were divided into four groups by CN size on MRI: bilateral AN with CN normalization (BAN Results: Totally 132 cases were included. The rate of CND was 35.6% (47/132), with 32.7% (36/110) and 50.0% (11/22) in bilateral and unilateral AN patients. The proportion of IAM I to IV grades increased progressively. Clinical and audiological characteristics differed between bilateral and unilateral AN patients. For bilateral AN patients, the age of onset and diagnosis of BAN Conclusion: The detection rate of CND was 35.6%, predominantly in unilateral AN patients and IAM IV was the most common type. Some clinical and audiological indicators were associated with imaging features of CN but varied between bilateral and unilateral AN. Variation in image performance may not be related to prognosis in AN patients.
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