ArticleFrontiers in cardiovascular medicine2025
Clinical performance of subcutaneous vs. transvenous implantable defibrillator in patients with ischemic cardiomyopathy:
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Subcutaneous ICD (S-ICD) is an alternative to a transvenous implantable cardioverter-defibrillator (TV-ICD) system in selected patients not in need of pacing or resynchronization. Currently, little is known about the effectiveness and safety of S-ICD in patients with ischemic cardiomyopathy (ICM). The aim of our study was to describe the clinical features and the drivers of S-ICD implantation among patients with ICM, as well as the clinical performance of S-ICD vs. TV-ICD among this subset of patients during a long-term follow-up. Materials and methods: All ICM patients with both S-ICD and TV-ICD implanted and followed at Monaldi Hospital from January 1, 2015, to January 1, 2024, were evaluated; among them, only ICD recipients with no pacing indication were included. We collected clinical and anamnestic characteristics, as well as ICD inappropriate therapies, ICD-related complications and infections. Results: A total of 243 ICM patients (mean age 63.0 ± 11.0, male 86.0%) implanted with TV-ICD ( Conclusions: Among patients with ICM not in need of pacing or resynchronization (CRT), the decision to implant an S-ICD was primarily influenced by female gender and primary prevention indications. No significant differences in inappropriate ICD therapies and complications were found; in contrast, the S-ICD group showed a numerically reduced risk of ICD-related infections.
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