Evidence map›Paper›PMID 40046941›Full record

ArticleDEN open2025

Difficult biliary cannulation during endoscopic retrograde cholangiopancreatography for distal malignant biliary obstruction caused by pancreatic cancer: An observational study.

Jun Noda, Yuichi Takano, Naoki Tamai, Masataka Yamawaki, Tetsushi Azami, Fumitaka Niiya, Naotaka Maruoka, Masatsugu Nagahama

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jun NodaDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.ORCID https://orcid.org/0009-0006-1254-9246
Yuichi TakanoDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0001-6803-9460
Naoki TamaiDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Masataka YamawakiDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Tetsushi AzamiDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Fumitaka NiiyaDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Naotaka MaruokaDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Masatsugu NagahamaDepartment of Internal Medicine, Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Distal malignant biliary obstruction (DMBO) caused by pancreatic cancer often complicates endoscopic retrograde cholangiopancreatography (ERCP), particularly biliary cannulation. While various factors influencing difficult biliary cannulation (DBC) have been studied, data specific to pancreatic cancer-related distant malignant biliary obstruction#x000A0;remains limited. This study identifies factors affecting ERCP success in this patient population to improve clinical outcomes. Methods: We retrospectively analyzed 119 ERCP procedures for distant malignant biliary obstruction owing to pancreatic cancer with naïve papilla at Showa University Fujigaoka Hospital (January 2020-September 2024). Patient characteristics, duodenal invasion, ampullary bile duct status, papillary morphology, trainee involvement, and adverse events were evaluated. Multivariate analysis identified predictive factors of DBC. Results: After excluding 17 ERCP failures, 102 patients were analyzed and categorized into non-DBC ( Conclusions: The absence of the ampullary bile duct and type III papillary morphology are anatomical risk factors for DBC during ERCP for patients with pancreatic cancer. Early consideration of alternative cannulation techniques or biliary drainage methods may be necessary for such patients.

Indexed as

bile ductscholangiopancreatographydrainagepancreatic carcinomaretrospective studies

Identifiers

PMID40046941
PMCPMC11880624

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.