ArticleFrontiers in medicine2025
Utility of the combination of IVIM-DWI MRI and baseline eGFR for identifying a high risk of chronic kidney disease progression.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Integrating kidney imaging for risk prediction, therapeutic monitoring, and prognostication across the kidney disease spectrum: a review of emerging evidence.Clinical kidney journal · 2026Review
- Assessment of renal interstitial fibrosis in glomerulonephritis using compartmental and non-compartmental diffusion magnetic resonance imaging.La Radiologia medica · 2026Article
- Cardiac-Gated Diffusion-Weighted Magnetic Resonance Imaging Assessment of Kidney Function in Patients With Kidney Cancer.Kidney international reports · 2026Article
- Article
- Exploring the Value of Functional Magnetic Resonance Imaging in Assessing Subclinical Rejection in Kidney Transplantation.Kidney diseases (Basel, Switzerland)Article
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8 authors.
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Abstract
Background: Currently, the baseline estimated glomerular filtration rate (eGFR), the urine albumin level and renal fibrosis are the common risk and prognostic factors for chronic kidney disease (CKD). Intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) is a proven noninvasive tool for assessing renal fibrosis. The aim of this study was to evaluate whether IVIM-DWI could be used to identify high-risk patients with CKD during long-term follow-up. Methods: In this exploratory study, 62 CKD patients who were followed for 5 years and who underwent renal biopsy and IVIM-DWI magnetic resonance imaging (MRI) at the National Clinical Research Center of Kidney Disease in China were enrolled. We recorded baseline data, including clinical, pathology and MRI parameters, and evaluated the associations between baseline parameters and renal outcomes. The value of DWI parameters in predicting end-stage kidney disease (ESKD) was compared with that of clinical and pathological data. Results: The mean baseline eGFR was 78.1 ± 28.05 ml/min/1.73 m Conclusion: The combination of baseline eGFR and IVIM-DWI outperforms pathological factors alone in the diagnosis of long-term kidney dysfunction. This study indicated that IVIM-DWI could be a promising tool for identifying patients at high risk of CKD progression.
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