Evidence map›Paper›PMID 40046919›Full record

ArticleFrontiers in medicine2025

Fibrinogen-to-albumin ratio: a new biomarker to identify inflammatory bowel disease in active stage.

Xiao-Fu Chen, Zhi-Ming Huang, Xie-Lin Huang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiao-Fu ChenCenter for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, China.
Zhi-Ming HuangDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xie-Lin HuangDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The objective of our study was to externally validate the value of the fibrinogen-to-albumin ratio (FAR), a new biomarker used to identify active inflammatory bowel disease (IBD). Materials and methods: A total of 245 ulcerative colitis (UC) and 543 Crohn's disease (CD) patients were included in our study. Multivariate logistic regression analysis was used to investigate the independent association between FAR and disease activity in patients with UC or CD. The area under the receiver operating characteristic curve was used to assess the prediction accuracy of biomarkers in distinguishing disease states. Results: Multivariate logistic regression analysis identified the FAR as the strongest predictor to discriminate disease activity of UC (odds ratio: 24.871, 95% confidence interval: 9.831-38.912, Conclusion: The FAR, a simple prognostic indicator, performs well in identifying active IBD.

Indexed as

activityalbuminbiomarkerfibrinogeninflammatory bowel disease

Identifiers

PMID40046919
PMCPMC11879998

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.