Evidence map›Paper›PMID 40046884›Full record

ArticleOpen forum infectious diseases2025

Clinicodemographic and Radiological Features of Infective Ring-Enhancing Brain Lesions: A 4-Year Retrospective Study at a Tertiary Referral Center.

Edwin Chong Yu Sng, Ling Ling Chan, Edwin Philip Conceicao, Min Jia Wong, Dorothy Hui Lin Ng, Hwee Kuan Lee, Candice Yuen Yue Chan

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edwin Chong Yu SngDepartment of Infectious Diseases, Changi General Hospital, Singapore.ORCID https://orcid.org/0000-0001-6522-2614
Ling Ling ChanDepartment of Diagnostic Radiology, Singapore General Hospital, Singapore.ORCID https://orcid.org/0000-0001-7603-7334
Edwin Philip ConceicaoDepartment of Infection Control, Changi General Hospital, Singapore.
Min Jia WongDepartment of Diagnostic Radiology, Singapore General Hospital, Singapore.
Dorothy Hui Lin NgDuke-NUS Medical School, Singapore.ORCID https://orcid.org/0000-0002-9059-5057
Hwee Kuan LeeBioinformatics Institute, A*STAR, Singapore.ORCID https://orcid.org/0000-0003-1932-5377
Candice Yuen Yue ChanDuke-NUS Medical School, Singapore.ORCID https://orcid.org/0000-0002-7321-710X

Funding

Can drug targets from parasitic nematodes be usefully expressed in C. elegans?R21AI092022 · NIAID · UNIVERSITY OF GEORGIA · PI WOLSTENHOLME, ADRIAN J · 2012 to 2013
$420k
NIAID NIH HHS R21 AI092022
6 · The paper itself

Abstract

Background: The diagnostic evaluation of ring-enhancing brain lesions (REBLs) is challenging, especially in immunocompromised patients. We conducted a retrospective study to describe the clinicodemographic and radiological features among patients presenting with REBLs to a tertiary referral center. Methods: Radiological reports of all patients who underwent brain computed tomography or magnetic resonance (MR) imaging between 1 November 2013 and 31 October 2017 were filtered for terms indicative of REBLs. Infectious diseases physicians reviewed the medical records to confirm the diagnosis. Results: Over the 4-year study period, there were 42 patients with infective REBLs and 249 with neoplastic REBLs. Pyogenic brain abscesses (PBAs) (20 of 42 [47.6%]) were the most common cause of infective REBLs, followed by tuberculous brain abscesses (TBAs) (9 of 42 [21.4%]) and Conclusions: Our study has revealed important distinguishing features between infective REBLs and neoplastic REBLs and between PBAs, TBAs, and NBAs.

Indexed as

Nocardiapyogenic brain abscessrim-enhancingring-enhancing brain lesionstuberculosis

Identifiers

PMID40046884
PMCPMC11879134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.