Evidence map›Paper›PMID 40046820›Full record

ArticleClinical kidney journal2025

Associations between initial dialysis access types and death from dialysis withdrawal in incident patients with kidney failure.

Jenny H C Chen, David W Johnson, Matthew A Roberts, Mark A Brown, Frank Brennan, Germaine Wong, Hicham Cheikh Hassan, Wing-Chi G Yeung, Alice Kennard, Christopher E Davies and 3 more

Abstract read
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In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jenny H C ChenDepartment of Renal Medicine, Wollongong Hospital, Wollongong, Australia.ORCID https://orcid.org/0000-0001-8900-2819
David W JohnsonDepartment of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Australia.
Matthew A RobertsSchool of Medicine, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0003-1665-3455
Mark A BrownDepartment of Nephrology, St George Hospital, Sydney, Australia.
Frank BrennanDepartment of Nephrology, St George Hospital, Sydney, Australia.
Germaine WongSydney School of Public Health, University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0001-8422-7269
Hicham Cheikh HassanDepartment of Renal Medicine, Wollongong Hospital, Wollongong, Australia.ORCID https://orcid.org/0000-0002-9198-6092
Wing-Chi G YeungDepartment of Renal Medicine, Wollongong Hospital, Wollongong, Australia.
Alice KennardSchool of Medicine, Australian National University, Canberra, Australia.
Christopher E DaviesAustralia and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia.
Neil BoudvilleMedical School, University of Western Australia, Perth, Australia.
Charmaine E LokDepartment of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada.
Wai H LimMedical School, University of Western Australia, Perth, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients receiving haemodialysis via a central venous catheter (HD-CVC) have been shown to have an increased risk of all-cause mortality. It is unclear whether death from dialysis withdrawal is associated with the high mortality risk observed in patients initiated on HD-CVC. Methods: Using the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, we examined the association between initial dialysis access [HD-CVC, haemodialysis via arteriovenous fistula (HD-AVF), and peritoneal dialysis (PD) via PD catheter (PD-PDC)] and death from dialysis withdrawal in adult patients starting dialysis in Australia between 2005 and 2022, analysed by time-stratified adjusted Cox regression with propensity score-matched cohorts. Results: Of 47 412 incident patients followed for a median of 2.65 years (interquartile range 1.19-4.87), 8170 (17%) died from dialysis withdrawal. Compared with patients initiated on HD-AVF, patients initiated on HD-CVC were more likely to experience death from dialysis withdrawal in the first 3 years after dialysis initiation, but not after 3 years [adjusted hazard ratios 2.43 (95% confidence interval 1.95-3.02), 2.06 (1.67-2.53), 1.57 (1.40-1.76), and 1.06 (0.97-1.15) for 0-6 months, >6-12 months, >1-3 years, and >3 years after dialysis initiation, respectively]. Comparison between patients initiated on HD-CVD and PD-PDC showed similar estimates. No difference in withdrawal risk was observed between patients initiated on HD-AVF and PD-PDC. Conclusions: Patients initiated on HD-CVC were twice as likely to experience early death from dialysis withdrawal compared with patients who had initiated dialysis with HD-AVF or PD-PDC. The increased risks diminished over time and were not observed after 3 years on dialysis.

Indexed as

arteriovenous fistulacatheterdialysismortalitywithdrawal

Identifiers

PMID40046820
PMCPMC11879430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.