ArticleInternational journal of preventive medicine2025
Diagnostic Value of Mean Platelet Volume, Neutrophil-to-Lymphocyte Ratio, and Platelet to Lymphocyte Ratio for Late-Onset Neonatal Sepsis.
Article in International journal of preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exploring the Inflammatory Basis of Endometrial Polyps: Clinical Implications of Hematological Biomarkers in a Retrospective Study.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Neonatal sepsis (NS) is the most common cause of neonatal mortality, currently confirmed with blood culture as the diagnostic gold standard. However, being time-consuming, false-negative results, being affected by even a single dose of antibiotics, and expensiveness are negative aspects. Therefore, we aimed to investigate the diagnostic value of complete blood count (CBC) parameters: mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) which have been suggested in previous studies. Methods: A total of 100 term and preterm neonates (age ≥ 32 weeks) hospitalized in Alzahra and Shahid Beheshti hospitals in Isfahan, Iran, were studied. Fifty neonates with late neonatal sepsis were placed in the case group, and 50 neonates with other diagnoses were placed in the control group. Neonatal blood samples were sent to the laboratory, and MPV, NLR, and PLR were measured. Results: The mean (standard deviation) of MPV was 7.20 (4.39) in the case group and 9.55 (0.87) in the control group, and there was a significant difference between them ( Conclusions: MPV, unlike NLR and PLR, can be used as a sensitive and cost-effective primary screening index in late NS at the cutoff point of 8.25 due. However, low specificity suggests a poor diagnostic value.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.