Evidence map›Paper›PMID 40046667›Full record

ArticleRoyal Society open science2025

Provide proactive reproducible analysis transparency with every publication.

Paul Meijer, Nicole Howard, Jessica Liang, Autumn Kelsey, Sathya Subramanian, Ed Johnson, Paul Mariz, James Harvey, Madeline Ambrose, Vitalii Tereshchenko and 15 more

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Paul MeijerAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.ORCID https://orcid.org/0000-0001-5535-0399
Nicole HowardAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Jessica LiangAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Autumn KelseyAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Sathya SubramanianAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Ed JohnsonAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Paul MarizAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
James HarveyAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Madeline AmbroseAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Vitalii TereshchenkoAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Aldan BeaubienAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Neelima InalaAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Yousef AggouneAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Stark PisterAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Anne VettoAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Melissa KinseyAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Tom BumolAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Ananda GoldrathAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Xiaojun LiAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Troy TorgersonAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Peter SkeneAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Lauren OkadaAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Christian La FranceAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Zach ThomsonAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.
Lucas GraybuckAllen Institute for Immunology, 615 Westlake Avenue N, Seattle, WA 98109, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large datasets, a granular understanding of the analysis methodology is an essential component of reproducibility. This article discusses the guiding principles of a computational reproducibility framework that enables a scientist to proactively generate a complete reproducible trace as analysis unfolds, and share data, methods and executable tools as part of a scientific publication, allowing other researchers to verify results and easily re-execute the steps of the scientific investigation.

Indexed as

data analysisequity in scienceimmunologylife sciencesopen sciencereproducibility crisis

Identifiers

PMID40046667
PMCPMC11879615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.