Evidence map›Paper›PMID 40046596›Full record

ArticleThe Brown journal of hospital medicine2022

Acute Esophageal Necrosis and Valproate Induced Acute Pancreatitis in a COVID-19 Patient.

Mohammad Abu-Abaa, Om Amin, Daniel Goldsmith

Abstract readCase Reports
In one paragraph

Article in The Brown journal of hospital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohammad Abu-AbaaDepartment of Medicine Capital Health Regional Medical Center, Trenton, NJ, USA.ORCID https://orcid.org/0000-0003-1752-1235
Om AminDepartment of Medicine Capital Health Regional Medical Center, Trenton, NJ, USA.
Daniel GoldsmithDepartment of Medicine Capital Health Regional Medical Center, Trenton, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 76-year-old man with a history of hypertension and chronic kidney disease presented with COVID-19 infection, hyperactive delirium, acute kidney injury, and hypotension. He developed acute pancreatitis as a complication of valproate therapy used to treat agitation. Poor oral intake, new onset dysphagia, hematemesis and lactic acidosis led to the diagnosis of acute esophageal necrosis on esophagogastroduodenoscopy (EGD). Valproate-induced pancreatitis is a rare complication and is more common in children and young adults. Acute esophageal necrosis, characterized by circumferential, black-appearing, distal esophageal mucosa, is associated with hypoperfusion and acid reflux.

Indexed as

acute esophageal necrosisblack esophagusCOVID-19pancreatitisValproatevalproic acid

Identifiers

PMID40046596
PMCPMC11878806

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.