ArticleAnnals of gastroenterological surgery2025
Liver resection in patients with a history of local ablation for hepatocellular carcinoma has the risk of poor survival and serosal invasion.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Comparing neoadjuvant targeted therapy plus transarterial chemoembolization versus triple therapy including immunotherapy in hepatocellular carcinoma: a Chinese multicentre study.Cancer immunology, immunotherapy : CII · 2025Article
- Liver resection in patients with a history of local ablation for hepatocellular carcinoma has the risk of poor survival and serosal invasion.Annals of gastroenterological surgery · 2025Article
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10 authors.
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Abstract
Aim: The aim was to evaluate the impact of previous local ablation (LA) on long-term prognoses and tumor histopathological findings following hepatectomy for hepatocellular carcinoma (HCC). Methods: This retrospective study used data from patients who underwent initial hepatectomy for HCC at Ehime University Hospital between October 2003 and July 2021. Using data from a total of 234 patients, after excluding patients with distant metastasis or macroscopic residual tumors and patients with mixed HCC, a group of 39 patients who underwent post-ablation liver resection (PALR) was compared with a group of 195 non-PALR patients with respect to patient characteristics, perioperative data, pathological findings, and outcomes. Results: Number of tumors was significantly greater and diameter of tumor was smaller in PALR group than those of non-PALR group. Both overall survival (OS) and recurrence-free survival (RFS) were significantly poor in PALR group than those of non-PALR (5-year OS 54.1% vs. 66.9%, Conclusions: Hepatectomy for patients with history of LA for HCC had a risk of serosal invasion and poor survival.
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