ArticleCureus2025
Evaluation of the Antibacterial and Antifungal Efficacy of Chitosan Nanoparticles in Irreversible Hydrocolloid Impression Materials: A Cross-Sectional Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The influence of chlorogenic acid disinfection on the oral microbiota of alginate impressions.Journal of oral microbiology · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIrreversible hydrocolloid (IHC) impression materials are widely used in dentistry for diagnostic impressions; however, they pose a risk of cross-contamination. Current cleaning methods such as rinsing with water may not be sufficient for effective disinfection. Incorporation of antimicrobial agents into IHC materials can reduce this risk. Chitosan, a biopolymer with proven antibacterial and antifungal properties, has potential as a self-disinfecting agent for IHC materials. This study aimed to evaluate the antibacterial and antifungal efficacy of chitosan nanoparticles (CHN) incorporated into IHC (alginate) impression materials. MATERIALS AND
methodsThis cross-sectional study was conducted in the Department of Prosthodontics, at the Surendera Dental College and Research Institute, Sri Ganganagar, Rajasthan, India, with 20 dentulous patients. A 1% CHN was incorporated into the IHC impression material to serve as Group 1, while conventional alginate mixed with distilled water with a one-week interval between each impression served as Group 2. Impressions were made on patients' maxillary arches, with bacterial and fungal samples collected at 0- and 10-minute intervals after rinsing the impressions. The samples were cultured on nutrient agar and Sabouraud dextrose agar for bacteria and fungi, respectively. Colony counts were assessed and statistically analyzed.
resultsThe study found a significant reduction in both bacterial and fungal counts in impressions made with Group 1 compared with Group 2 at both 0- and 10-minute intervals (p<0.001). At 10 minutes, bacterial counts decreased significantly in Group 1 (from 75.50±34.56 to 26.00±16.03), and fungal counts were also reduced (from 2.70±1.22 to 0.55±0.69). The antibacterial and antifungal efficacy was increased at the 10-minute interval, compared to the 0-minute interval. Conclusion: Incorporating 1% CHN into the IHC impression material significantly enhanced its antibacterial and antifungal properties, making it an effective self-disinfecting agent. This modification reduces the need for additional disinfection steps and offers a practical solution for improving cross-infection control in dental practice. CHN's biocompatibility and biodegradability further support its potential as an eco-friendly and sustainable alternative for dental materials.
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