Evidence map›Paper›PMID 40046353›Full record

ArticleCureus2025

Clinical and Therapeutic Characteristics of Stroke and Their Implications on Outcomes: A Multi-center Study in Panama.

Erick Villarreal, Harry Wolfschoon, Abdullah Salehji, Kayra Patiño, Denise Cardoze, Verónica Billingslea, Esteban González, Astrid Batista

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erick VillarrealFaculty of Medicine, Universidad de Panamá, Panama, PAN.
Harry WolfschoonFaculty of Medicine, Universidad de Panamá, Panama, PAN.
Abdullah SalehjiDepartment of Hematology, Ciudad de la Salud, Caja del Seguro Social, Panama, PAN.
Kayra PatiñoDepartment of Geriatrics, Complejo Hospitalario Metropolitano Dr. Arnulfo Arias Madrid, Caja del Seguro Social, Panama, PAN.
Denise CardozeDepartment of Nephrology, Ciudad de la Salud, Caja del Seguro Social, Panama, PAN.
Verónica BillingsleaDepartment of Neurology, Ciudad de la Salud, Caja del Seguro Social, Panama, PAN.
Esteban GonzálezDepartment of Internal Medicine, Hospital Gustavo Nelson Collado, Caja del Seguro Social, Chitré, PAN.
Astrid BatistaDepartment of Internal Medicine, Hospital Gustavo Nelson Collado, Caja del Seguro Social, Chitré, PAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction There are no previous studies that assess the time between stroke symptom onset and hospital arrival in Panama. With this study, we aim to describe the epidemiological, clinical, and therapeutic characteristics of the patients to determine whether our data on stroke care and outcomes align with those from other Latin American countries and nations with more advanced healthcare systems. Methods This prospective study included 214 stroke patients admitted to three healthcare centers in Panama between January and December 2023. Demographic, clinical, and therapeutic data were collected using a standardized instrument. Univariate analysis was then conducted in order to describe patient characteristics and their distribution across outcomes, which included discharge, critical care unit transfer, or death. Results Out of the 214 patients included in the study, 124 (57%) were men, and 88 (42%) were women. The main risk factors were arterial hypertension, type 2 diabetes, and previous history of stroke. The overall median time from symptom onset to arrival was 10 hours, and the median National Institutes of Health Stroke Scale (NIHSS) score on arrival was 5. The mean hospital stay was 10.4 days, and overall mortality was 38 (17.7%). Only five (2%) patients were able to receive intravenous thrombolysis. Discussion This study is the first to report the time from stroke symptom onset to hospital arrival in Panama, with a median recorded time of 10 hours. Despite national improvements in the length of stay and overall mortality, the negative results displayed by our study may be explained by the significant strain public hospitals face due to the high demand for their services. Conclusion The measured time in hours from symptom onset to arrival at a healthcare center across three centers in Panama was 10 hours, and thrombolysis was only recorded in five (2%) cases. Results reveal notable regional disparities and prompt further research on effective improvement strategies.

Indexed as

hemorrhagic strokeinpatient mortality rateintravenous thrombolysisischemic strokelength of stayoutcomesrisk factorsstroke

Identifiers

PMID40046353
PMCPMC11882105

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