Evidence map›Paper›PMID 40046337›Full record

ArticleBrain communications2025

MRI identifies disrupted cerebral development in medulloblastoma patients.

Asim K Bag, Joseph Holtrop, John O Glass, Samuel S McAfee, Shengjie Wu, Yimei Li, Matthew Scoggins, Silu Zhang, Giles W Robinson, Amar Gajjar and 3 more

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Asim K BagRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Joseph HoltropRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
John O GlassRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Samuel S McAfeeRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID https://orcid.org/0000-0003-4121-0592
Shengjie WuBiostatistics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Yimei LiBiostatistics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Matthew ScogginsRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Silu ZhangRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID https://orcid.org/0000-0001-5336-5650
Giles W RobinsonOncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Amar GajjarOncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID https://orcid.org/0000-0001-5019-0699
Tara M BrinkmanPsychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Heather M ConklinPsychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID https://orcid.org/0000-0001-8931-4134
Wilburn E ReddickRadiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive decline in survivors of medulloblastoma is commonly attributed to radiation- and chemotherapy-induced brain microstructural alterations. Factors preceding this adjuvant therapy, such as disrupted brain development or resection surgery, may affect brain microstructure but have not been thoroughly explored in medulloblastoma. The aim of this study was to assess cortical thickness and microstructural integrity of the cerebrum prior to adjuvant therapy in medulloblastoma patients. Cross-sectional image data were acquired of medulloblastoma patients (

Indexed as

brain developmentDTImedulloblastomaMRI

Identifiers

PMID40046337
PMCPMC11879392

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.