ArticleThe Brown journal of hospital medicine2023
Hypercalcemia as the Presenting Finding in VIPoma.
Article in The Brown journal of hospital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Hypercalcemia is typically associated with primary hyperparathyroidism, malignancy, vitamin D intoxication, and granulomatous disease; however, it can also be associated with a neuroendocrine tumor that secretes vasoactive intestinal polypeptide (VIP). A 74-year-old woman with a history of hypothyroidism and nephrolithiasis presented to her primary care physician with a chief complaint of diarrhea and was found to have mild hypercalcemia. A Hypercalcemia workup was initiated, and the patient was ultimately found to have elevated VIP. Although a discrete pancreatic mass was not identified, an endoscopic ultrasound with fine needle aspiration revealed a VIPoma. She was then referred to hepatobiliary surgery for the removal of the tumor. As VIPoma has a poor prognosis, early recognition and treatment are essential for improving patient outcomes.
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