ArticleFrontiers in public health2025
Determining the impact of the COVID-19 pandemic on the consumption of antibiotics in Shaanxi province, China: an interrupted time-series analysis.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Comparative Trends in Human and Veterinary Antimicrobial Consumption in the European Union, 2019-2024.Antibiotics (Basel, Switzerland) · 2026Review
- Burden of bacterial antimicrobial resistance in China: a systematic analysis from 1990 to 2021 and projections to 2050.Journal of advanced research · 2026Article
- A comprehensive descriptive, predictive, and prescriptive analysis of antibiotic products' demand pre-, amid, and post-COVID-19 in Iran.Scientific reports · 2025Article
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Authors and funding
9 authors.
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Abstract
Background: The COVID-19 pandemic, as well as associated prevention and control measures, have impacted the entire healthcare system, including the use patterns of medicine. However, the impact of COVID-19 on the use of antibiotics has not yet been extensively evaluated in China. This study aimed to evaluate the impact of the pandemic on the consumption and expenditure of antibiotics in public healthcare institutions in Shaanxi Province, China. Methods: We used longitudinal data from the Shaanxi provincial drug procurement database in this study. An interrupted time-series analysis was performed to evaluate the effects of COVID-19 on consumption and expenditures of antibiotics in public healthcare institutions in Shaanxi from 1 January 2017 to 31 December 2020. Antibiotic consumption was expressed as the number of defined daily doses (DDDs) per 1,000 residents per day (DIDs), based on the population of Shaanxi Province at the end of each year from the National Bureau of Statistics. The pre-pandemic period was from January 2017 to January 2020, and the post-pandemic period was from February 2020 to December 2020. Results: A declining trend in antibiotic consumption was observed immediately following the COVID-19 pandemic ( Conclusion: Despite an initial decline in antibiotic consumption at the start of the COVID-19 pandemic, it had returned to prior levels by the end of 2020. Findings underscore the continued importance of antibiotic stewardship initiatives.
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