Evidence map›Paper›PMID 40046087›Full record

ArticleSchizophrenia research. Cognition2025

The awareness, characterization, and burden of Cognitive Impairment Associated with Schizophrenia (CIAS) in clinical practice: Results from a nationwide survey in Italy.

Antonio Vita, Stefano Barlati, Roberto Cavallaro, Riccardo Cipelli, Giulio Corrivetti, Dario Delmonte, Eleonora Lusito, Elisabetta Maia, Maria Michela Marino, Giuseppe Nicolò and 2 more

Abstract read
In one paragraph

Article in Schizophrenia research. Cognition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Antonio VitaDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Stefano BarlatiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Roberto CavallaroDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Riccardo CipelliIQVIA Solutions Italy Srl, Milan, Italy.
Giulio CorrivettiDipartimento di Salute Mentale, ASL Salerno, Italy.
Dario DelmonteMedical Affairs, Boehringer-Ingelheim, Italy.
Eleonora LusitoIQVIA Solutions Italy Srl, Milan, Italy.
Elisabetta MaiaMedical Affairs, Boehringer-Ingelheim, Italy.
Maria Michela MarinoMedical Affairs, Boehringer-Ingelheim, Italy.
Giuseppe NicolòDipartimento di Salute Mentale, ASL Roma 5, Italy.
Paola RoccaDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, 10126 Turin, Italy.
Silvana GalderisiDepartment of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, 80138 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cognitive Impairment (CIAS) is a core aspect of schizophrenia and one of the main obstacles to clinical and functional recovery in patients. People with CIAS have difficulties with learning and using information in real world. Despite its well-recognized role, it is not yet a diagnostic criterion in DSM-5 and ICD system. The effective management of CIAS represents a critical unmet need of schizophrenia treatment. Methods: To evaluate the awareness of CIAS in the Italian landscape, we conducted a quantitative survey on psychiatrists highly specialized in schizophrenia, focused on its awareness, assessment, burden, and treatment. Results: Of 152 participants, 139 (91.4 %) consider CIAS assessment important. The terminology most frequently used to describe CIAS is 'cognitive impairment'. CIAS is assessed, clinically or with formal tools, in approximately 43 % of patients after stabilisation either during follow-up visits ( Conclusions: The clinical characteristics of the patient, structural barriers like the lack of trained personnel or inadequate economic resources, and organizational problems influence the assessment rate. Despite this awareness, greater effort must be made to overcome the barriers, especially economic and organizational ones, which prevent the assessment and treatment of CIAS from becoming established in routine clinical care.

Indexed as

AssessmentCIASCognitive remediationEvidence-basedPsychosocial functioningRecoverySchizophrenia

Identifiers

PMID40046087
PMCPMC11880602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.