Evidence map›Paper›PMID 40045995›Full record

ArticlePNAS nexus2025

Mechanistic and structural insights into the itaconate-producing

Liujuan Zheng, Wei Li, Marvin Christ, Nicole Paczia, Wolfgang Buckel, Christopher-Nils Mais, Michael Bölker, Johannes Freitag, Gert Bange

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular insights into the promiscuous ApThe Journal of biological chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liujuan ZhengMax-Planck Institute for Terrestrial Microbiology, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.
Wei LiDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.
Marvin ChristDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.
Nicole PacziaMax-Planck Institute for Terrestrial Microbiology, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.
Wolfgang BuckelDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.ORCID https://orcid.org/0000-0002-8280-1260
Christopher-Nils MaisDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.
Michael BölkerDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.ORCID https://orcid.org/0000-0002-7366-3855
Johannes FreitagDepartment of Chemistry and Biology and Center for Synthetic Microbiology (SYNMIKRO), University of Marburg, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.ORCID https://orcid.org/0000-0002-8251-4878
Gert BangeMax-Planck Institute for Terrestrial Microbiology, Karl-von-Frisch Strasse 14, Marburg 35043, Germany.ORCID https://orcid.org/0000-0002-7826-0932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Itaconic acid belongs to the high-value precursors for the production of biomass-based industrial compounds. It originates from the tricarboxylic acid cycle, and depending on the organism, it is produced by different biosynthetic routes. The basidiomycete fungus

Identifiers

PMID40045995
PMCPMC11880804

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.