Evidence map›Paper›PMID 40045846›Full record

ArticleJournal of medicinal chemistry2025

Supramolecular Partners: Precision On/Off Neuromuscular Blockage for Prolonged Surgeries.

Ziyi Wang, Hang Yin, Ruibing Wang

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ziyi WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, & Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR 999078, China.
Hang YinState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, & Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR 999078, China.ORCID 0000-0002-2898-844X
Ruibing WangState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, & Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR 999078, China.ORCID 0000-0001-9489-4241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a long-acting neuromuscular blocking agent and its on-demand reversal is highly desired for prolonged surgeries. This viewpoint discussed the discovery of supramolecular partners, an imidazolium-based macrocycle (YW70271) and acyclic cucurbit[n]uril (WY22051), for ultralong neuromuscular blockade and rapid reversal.

Indexed as

Bridged-Ring CompoundsImidazolesNeuromuscular BlockadeNeuromuscular Blocking AgentsAnimalsHumansBridged-Ring CompoundsImidazolesNeuromuscular Blocking Agents

Identifiers

PMID40045846
PMCPMC11997994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.