Evidence map›Paper›PMID 40045716›Full record

ArticleHuman vaccines & immunotherapeutics2025

Evaluating the impact of the vaccination prescription program on herpes zoster vaccine coverage in Ningbo, China: An interrupted time series analysis.

Jianmei Wang, Jiaxin Wang, Ning Li, Dongkai Du, Dandan Zhang, Rui Ma

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianmei WangDepartment of Immunization Program, Ningbo Municipal Center for Disease Prevention and Control, Ningbo, Zhejiang, China.
Jiaxin WangSchool of Public Health, Peking University, Beijing, China.
Ning LiDepartment of Immunization Program, Ningbo Municipal Center for Disease Prevention and Control, Ningbo, Zhejiang, China.
Dongkai DuSchool of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Dandan ZhangDepartment of Immunization Program, Ningbo Municipal Center for Disease Prevention and Control, Ningbo, Zhejiang, China.
Rui MaDepartment of Immunization Program, Ningbo Municipal Center for Disease Prevention and Control, Ningbo, Zhejiang, China.ORCID 0009-0006-2379-2313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the population ages, herpes zoster (HZ) and postherpetic neuralgia, which are associated with a substantial disease burden, are expected to increase. Ningbo began to implement the Vaccination Prescription Program for community individuals in April 2022. The anonymized HZ vaccination records of individuals aged above 50 during 2020-2023 were extracted from the Ningbo Immunization Information Management System. We applied interrupted time series analyses controlling for long-term trends and seasonality to assess the effects of the program on HZ vaccination coverage. Effect modification from demographic characteristics was investigated. Totally 18,133 doses of the HZ vaccine were administered. The cumulative coverage increased from 0.16‰ to 2.97‰, and the full series cumulative coverage from 0.04‰ to 2.48‰. Relatively higher coverage and full series coverage were observed among residents, females, individuals residing in inner districts and high socioeconomic regions, and those aged 50-59 years. During the transition period, a 468.7% increase in HZ vaccination coverage was evident (Rate Ratio [RR], 5.687; 95% Confidence Interval [CI], 2.334-13.857), and significant impact was detected among all demographic characteristics. During the post-implementation period, a 261.3% increase in coverage was evident (RR, 3.613; 95% CI, 1.202-10.858), while no effect was found among migrants, individuals living in regions with high socioeconomic status, and those aged above 70 years. Although the positive effect of the program, it is imperative to implement key strategies for providing affordable HZ vaccines, such as government funding, subsidies, and vaccination prescriptions from healthcare professionals, alongside peer initiatives and family members' education.

Indexed as

Herpes ZosterHerpes Zoster VaccineImmunization ProgramsVaccinationVaccination CoverageAgedAged, 80 and overChinaFemaleHumansInterrupted Time Series AnalysisMaleMiddle AgedNeuralgia, PostherpeticHerpes Zoster VaccinecoverageHerpes zosterherpes zoster vaccineimpactinterrupted time series analysisvaccination prescription program

Identifiers

PMID40045716
PMCPMC11901373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.