Evidence map›Paper›PMID 40045636›Full record

SynthesisEpidemiology and psychiatric sciences2025

Self-reports vs clinician ratings of efficacies of psychotherapies for depression: a meta-analysis of randomized trials.

Clara Miguel, Mathias Harrer, Eirini Karyotaki, Constantin Yves Plessen, Marketa Ciharova, Toshi A Furukawa, Ioana A Cristea, Pim Cuijpers

Abstract readMeta-Analysis
In one paragraph

Synthesis in Epidemiology and psychiatric sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effectiveness ofPsychological medicine · 2026
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  20. Effectiveness of a digital health application (Multiple sclerosis journal - experimental, translational and clinical
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clara MiguelDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.ORCID https://orcid.org/0000-0001-5563-5896
Mathias HarrerPsychology & Digital Mental Health Care, Technical University Munich, Munchen, Germany.
Eirini KaryotakiDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Constantin Yves PlessenDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Marketa CiharovaDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Toshi A FurukawaDepartment of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Kyoto, Japan.ORCID https://orcid.org/0000-0003-2159-3776
Ioana A CristeaDepartment of General Psychology, University of Padova, Padova, Italy.
Pim CuijpersDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.ORCID https://orcid.org/0000-0001-5497-2743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe comparability between self-reports and clinician-rated scales for measuring depression following treatment has been a long-standing debate, with studies finding mixed results. While the use of self-reports in psychotherapy trials is very common, it has been widely assumed that these tools pose a validity threat when masking of participants is not possible. We conducted a meta-analysis across randomized controlled trials (RCTs) of psychotherapy for depression to examine if treatment effect estimates obtained via self-reports differ from clinician-rated outcomes.

methodsWe identified studies from a living database of psychotherapies for depression (updated to 1 January 2023). We included RCTs measuring depression at post-treatment with both a self-report and a clinician-rated scale. As our main model, we ran a multilevel hierarchical meta-analysis, resulting in a pooled differential effect size (Δ

resultsA total of 91 trials (283 effect sizes) were included. In our main model, we found that self-reports produced smaller effect size estimates compared to clinician-rated instruments (Δ

conclusionsSelf-report instruments did not overestimate the effects of psychotherapy for depression and were generally more conservative than clinician assessments. Patients' perception of improvement should not be considered less valid by default, despite the inherent challenge of masking in psychotherapy.

Indexed as

DepressionPsychiatric Status Rating ScalesPsychotherapySelf ReportHumansRandomized Controlled Trials as TopicTreatment Outcomeblindingclinician-rated scalesdepression measurementpsychotherapyself-reports

Identifiers

PMID40045636
PMCPMC11886967

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.