Evidence map›Paper›PMID 40045617›Full record

ArticleAnimal bioscience2025

Effects of milk fortification with an advanced chelated trace minerals supplement on growth, health, and nutrient digestibility in dairy calves.

Hossein Rajaei-Sharifabadi, Hadi Rahmani, Zahra Shokri, Saideh Fakharzadeh, Somayeh Kalanaky, Mohammad Hassan Nazaran, Ahmad Reza Seradj

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Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Hossein Rajaei-SharifabadiDepartment of Animal Science, Faculty of Agriculture, Malayer University, Malayer, Iran.
Hadi RahmaniDepartment of Animal Science, Faculty of Agriculture, Malayer University, Malayer, Iran.
Zahra ShokriDepartment of Animal Science, Faculty of Agriculture, Malayer University, Malayer, Iran.
Saideh FakharzadehDepartment of Animal Science, Universitat de Lleida, Lleida, Spain.
Somayeh KalanakyDepartment of Animal Science, Universitat de Lleida, Lleida, Spain.
Mohammad Hassan NazaranDepartment of Animal Science, Universitat de Lleida, Lleida, Spain.
Ahmad Reza SeradjDepartment of Research and Development, Sodour Ahrar Shargh Co., Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent advancements in chelate compound technology offer improved bioavailability of trace minerals, potentially enhancing growth performance and reducing disease incidence. Milk fortification is an efficient method to supplement young calves before transition to solid feed. This study evaluated the response of dairy calves to milk fortification with an advanced chelated trace minerals supplement containing Zn, Mn, Cu, Fe, Co, Cr, and Se, each selected for their specific roles in calf development, synthesized using chelate compoundtechnology.

methodsForty-two Holstein dairy calves (21 males and 21 females) were randomly assigned to three experimental groups: control (CON, unfortified milk), chelated minerals (BON, milk fortified with chelated trace minerals), and inorganic minerals (IOR, milk fortified with inorganic trace minerals). Calves received their respective milk treatments daily from d 3 until weaning at 70 d of age. Growth performance and body measurements were assessed throughout the experiment, while rectal temperature, fecal consistency, and frequency of medical treatment were recorded until d 21. Blood metabolites and nutrient digestibility were also determined.

resultsBON supplementation resulted in 9% body weight increase (p = 0.027) and improved some body measurements (p<0.05). The calves in BON group showed a lower fecal consistency index (p<0.05) and required fewer medical treatments compared to CON and IOR (p = 0.103). Blood analysis revealed 27% reduction in globulin levels (p = 0.022), 10% increase in albumin levels (p = 0.023) and a 42% elevation in albumin/globulin ratio (p = 0.042) in BON compared to the CON groups. The activities of liver enzymes were higher in IOR than in the BON and CON group.

conclusionMilk fortification with advanced chelated trace minerals significantly enhanced growth performance and health indicators in dairy calves, while inorganic sources showed no beneficial effects. These findings establish the superiority of chelated mineral supplementation for early-life dairy calf development;nevertheless, appropriate supplementation procedures require additional experiments.

Indexed as

Advanced Chelate Compounds TechnologyBody MeasurementsFecal ConsistencyMedical TreatmentOrganic Trace Minerals

Identifiers

PMID40045617
PMCPMC12229941

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