Evidence map›Paper›PMID 40045616›Full record

ArticleAnimal bioscience2025

Change in adipose tissue characteristics and lipid metabolism in natural grazing Mongolian cattle with age.

Xueting Yu, Lu Chen, Xige He, Yunfei Han, Yajuan Huang, Rina Sha, Gerelt Borjigin

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PubMed Full text at PMC Publisher
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Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueting YuCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.
Lu ChenCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.
Xige HeCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.
Yunfei HanInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Yajuan HuangCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.
Rina ShaCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.
Gerelt BorjiginCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, China.

Funding

National Nature Science Foundation of China 32260556
6 · The paper itself

Abstract

objectiveThis study aimed to elucidate the lipid composition, characteristics, and metabolic mechanisms of subcutaneous adipose tissue (SAT) in natural grazing Mongolian cattle during its development.

methodsThe experimental animals consisted of castrated Mongolian cattle, divided into two groups: 10 months old (10 M, n = 12, average weight: 113.26±0.87 kg) and 34 months old (34 M, n = 12, average weight: 390.44±1.23 kg). All animals were selected from the same herd in the Eren Nur grasslands, Xilingol, Inner Mongolia, China. Browning-related genes in SAT were determined using quantitative reverse transcription polymerase chain reaction with 3 replicates for each cattle, and six animals from each group were randomly selected for non-targeted lipidomic techniques to analyze the changes in lipid metabolism with 6 replicates.

resultsThe yellowness value and relative expression of mitochondrial biogenesis-specific markers, thermogenic markers, uncoupling protein-2 (UCP2), and beige adipocyte marker genes in the SAT increased with age. Multivariate analysis revealed 172 significantly different lipids (SDLs). Triacylglycerols and phosphatidylcholines showed high relative contents. Glycerol and sterol lipid levels were predominantly upregulated during development, whereas phospholipids and sphingolipids were primarily upregulated at 10 M. Developmental time greatly influenced the fatty acid composition of neutral lipids, phospholipids, and free fatty acids. Pathway analysis demonstrated that the 172 SDLs were primarily involved in glycerophospholipid, glycerolipid, ether lipid, and sphingolipid metabolism.

conclusionThe developmental stage significantly affected the lipid quantity, composition, and metabolism of SAT in Mongolian cattle. Certain functional lipids, such as mediumlong-chain triglycerides, fatty acid ester of hydroxyl fatty acid, and vitamin D, were detected in the yellow fat of natural grazing Mongolian cattle. These findings provide a comprehensive reference for the metabolic characteristics of yellow fat in Mongolian cattle, contributing to the meat industry chain.

Indexed as

LipidsMetaboliteMongolian CattleSubcutaneous Fat

Identifiers

PMID40045616
PMCPMC12229929

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