ArticleAnimal bioscience2025
Effects of low-purine diet supplemented with Sida acuta Burm. f. on growth performance, purine deposition, and biomolecules in slow-growing chickens.
Article in Animal bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effects of dihydroorotate dehydrogenase inhibition and vitamin E supplementation on ferroptosis-related mechanisms and post-mortem meat quality in broiler chickens.Animal bioscience · 2026Article
- Effects of Different Packaging on the Purine Content and Key Enzymes of Refrigerated Yellow Croaker (Foods (Basel, Switzerland) · 2025Article
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5 authors.
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Abstract
objectiveThis study investigated the effects of a low-purine (Pu) diet supplemented with Sida acuta Burm. f. (SA) on growth performance, serum uric acid (SUA), and meat quality, including chemical composition, biomolecules, and purine deposition, in slow-growing Korat chickens (KRC).
methodsA total of 480 mixed-sex one-d-old KRC were randomly allocated into five groups with six replicates each (16 chicks/replicate) using a 1+2×2 augmented factorial experiment in a completely randomized design. Five experimental diets were as follows: a control (basal diet), two diets with 30% and 45% lower purine levels than the control (-30% and -45% Pu), each supplemented with two levels of SA (0.3% and 0.6% SA), respectively. After sex determination, all subsequent analyses were conducted exclusively on female birds.
resultsKRC fed a -30% Pu diet supplemented with 0.6% SA showed reduced hypoxanthine and total purine deposition in major breast muscle (Pectoralis majora) without negative effects on growth performance, SUA levels, meat quality, chemical composition, biomolecules, and protein secondary structures comparable to the control group. Birds fed a -45% Pu diet, supplemented with either 0.3% or 0.6% SA, exhibited impaired growth performance and without significant changes in major breast muscle hypoxanthine or total purine content. Correlation analysis revealed that the -30% Pu diet supplemented with 0.6% SA was positively correlated with reduced hypoxanthine and total purine content, while showing negative correlations with lipid content and β-turn structure.
conclusionA 30% reduction in dietary purines combined with 0.6% SA supplementation effectively decreased purine deposition in chicken meat, contributing to the production of healthier chicken meat product. Further studies are needed to investigate the molecular mechanisms and metabolic pathways, which will enable breeders to advance the development of Pu chicken meat production.
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