Evidence map›Paper›PMID 40045492›Full record

ArticleMedicine and science in sports and exercise2025

Influence of Running Speed and Time Postoperatively on Lower Extremity Work in Collegiate Athletes after Anterior Cruciate Ligament Reconstruction.

Keith A Knurr, Daniel G Cobian, Stephanie A Kliethermes, Mikel R Joachim, Bryan C Heiderscheit

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Article in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Daniel G Cobian
Stephanie A Kliethermes
Mikel R Joachim
Bryan C Heiderscheit

Funding

Biology of Aging and Age-Related Diseases Training GrantT32AG000213 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Rozalyn M. Anderson, Sanjay Asthana · 1991 to 2026
$9.9M
NIA NIH HHS T32 AG000213
6 · The paper itself

Abstract

purposeFollowing anterior cruciate ligament reconstruction (ACLR), individuals present with significant and persistent deficits in surgical knee biomechanics during running. Little is known regarding the role of the hip and ankle in compensating for these knee-specific deficits. The purpose of this study was to characterize how limb (surgical and nonsurgical), time postoperatively (3.5-7 months [EARLY], 8-13 months [LATE]), and running speed influence lower extremity joint-specific and total work during running post-ACLR.

methodsFifty-six Division I collegiate athletes post-ACLR (EARLY: n = 41; LATE: n = 42; both: n = 27) completed running analyses at 2.68, 2.95, 3.35, 3.80, and 4.47 m·s -1 or up to their maximum comfortable speed. Linear mixed effects models assessed the influence of limb, speed, time post-ACLR, and their interactions on hip, knee, ankle, and total negative work and positive work.

resultsSurgical limb hip positive work was greater (0.044 J·kg -1 [95% CI = 0.015-0.074], P < 0.001) than the nonsurgical limb EARLY. Surgical limb ankle negative (-0.054 J·kg -1 [-0.093 to -0.015], P = 0.003) and positive work (-0.115 J·kg -1 [-0.168 to -0.063], P < 0.001) were less than the nonsurgical limb EARLY. Surgical limb knee negative (EARLY: -0.339 J·kg -1 [-0.382 to -0.296], P < 0.001; LATE: -0.222 J·kg -1 [-0.265 to -0.180], P < 0.001) and positive work (EARLY: -0.214 J·kg -1 [-0.246 to -0.182], P < 0.001; LATE: -0.142 J·kg -1 [-0.174 to -0.110], P < 0.001) were less than the nonsurgical limb. Total negative work and positive work followed the same pattern as the knee.

conclusionsAthletes post-ACLR exhibited greater hip positive work and lesser ankle positive work and negative work during running of the surgical limb EARLY, which resolved LATE. Both knee and total negative work and positive work of the surgical limb were substantially less than the nonsurgical limb, which improved from EARLY to LATE, but between-limb asymmetries remained.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionKnee JointLower ExtremityRunningAdolescentAnkle JointBiomechanical PhenomenaFemaleHipHip JointHumansMalePostoperative PeriodTime FactorsYoung AdultACLBIOMECHANICSCONTRIBUTIONJOINTKNEE

Identifiers

PMID40045492
PMCPMC12879010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.