SynthesisBMC cancer2025
Impact of single-port versus three-port video-assisted thoracic surgery lobectomy on postoperative pain and quality of life in early-stage non-small cell lung cancer patients: a meta-analysis.
Synthesis in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Postoperative chronic pain following uniport vs. multiport video-assisted thoracoscopic surgery: insights from a propensity score-matched analysis.Journal of anesthesia · 2026Article
- Case Series: Single-port subxiphoid robotic excision of ectopic mediastinal parathyroid adenomas.Frontiers in surgery · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis meta-analysis aims to evaluate the impact of these two techniques on postoperative pain and quality of life in early-stage NSCLC patients.
methodsA comprehensive literature search was conducted in PubMed, Cochrane Library, Web of Science, and CNKI databases. Randomized controlled trials and cohort studies comparing single-port and three-port VATS lobectomy for early-stage NSCLC were included. The primary outcomes were operating time, postoperative complications, and 24-hour postoperative visual analog scale (VAS) pain scores. The Newcastle-Ottawa Scale (NOS) was used to assess study quality. Meta-analysis was performed using random-effects models, and heterogeneity was assessed using the I² statistic.
resultsFifteen studies involving 3,228 patients (801 in the single-port group and 2427 in the three-port group) were included. The meta-analysis revealed that single-port VATS lobectomy was associated with a longer operating time (SMD: 0.61, 95% CI: 0.29 to 0.93, p < 0.001) compared to the three-port approach. However, single-port VATS demonstrated a lower incidence of postoperative complications (RR: 0.73, 95% CI: 0.59 to 0.90, p < 0.001). There was no significant difference in 24-hour postoperative VAS pain scores between the two groups (SMD: 0.02, 95% CI: -1.41 to 1.45, p > 0.05), although substantial heterogeneity was observed (I² = 98.1%).
conclusionThis meta-analysis suggests that single-port VATS lobectomy may offer advantages in terms of reduced postoperative complications compared to the three-port approach, despite longer operating times. However, the impact on immediate postoperative pain remains inconclusive due to high heterogeneity among studies.
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