Evidence map›Paper›PMID 40045216›Full record

ArticleBMC plant biology2025

Transcriptome analysis of wild olive (Olea Europaea L. subsp. europaea var. sylvestris) clone AC18 provides insight into the role of lignin as a constitutive defense mechanism underlying resistance to Verticillium wilt.

Beatriz Mascuñano, Jerónimo Coto-Elena, Víctor M Guerrero-Sánchez, Candelas Paniagua, Rosario Blanco-Portales, José L Caballero, José L Trapero-Casas, Rafael M Jiménez-Díaz, Fernando Pliego-Alfaro, José A Mercado and 2 more

Abstract read
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Beatriz MascuñanoDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain.
Jerónimo Coto-ElenaDepartamento de Botánica y Fisiología Vegetal, Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora' (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, 29071, Spain.
Víctor M Guerrero-SánchezDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain.
Candelas PaniaguaDepartamento de Botánica y Fisiología Vegetal, Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora' (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, 29071, Spain.
Rosario Blanco-PortalesDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain.
José L CaballeroDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain.
José L Trapero-CasasInstitute for Sustainable Agriculture, Spanish National Research Council (Consejo Superior de Investigaciones Científicas), Córdoba, Spain.
Rafael M Jiménez-DíazAgronomy Department, University of Córdoba, Edificio C4 Celestino Mutis. Campus de Rabanales, Córdoba, E-14014, Spain.
Fernando Pliego-AlfaroDepartamento de Botánica y Fisiología Vegetal, Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora' (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, 29071, Spain.
José A MercadoDepartamento de Botánica y Fisiología Vegetal, Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora' (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, 29071, Spain.
Juan Muñoz-BlancoDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain. bb1mublj@uco.es.
Francisco J Molina-HidalgoDepartment of Biochemistry and Molecular Biology, University of Cordoba, Edificio Severo Ochoa, Campus de Rabanales, Córdoba, E-14014, Spain. b52mohif@uco.es.

Funding

Andalusian Regional Council P18-RT-1933MCIN/AEI/10.13039/501100011033 and the European Union "NextGenerationEU"/PRTR. IJC2020-045526-I
6 · The paper itself

Abstract

Host resistance is the most effective and practical control method for the management of Verticillium wilt in olive caused by Verticillium dahliae, which remains as one of the major current threats to this crop. Regrettably, most olive cultivars of agronomic and commercial interest are susceptible to V. dahliae. We previously demonstrated that wild olive (Olea europaea L. subsp. europaea var. sylvestris) clone AC18 harbours resistance to the highly virulent defoliating (D) V. dahliae pathotype, which may be valuable as rootstock and for breeding new, resistant olive cultivars. Mechanisms underlying disease resistance may be of constitutive or induced nature. In this work we aim to unravel constitutive defences that may be involved in AC18 resistance, by comparing the transcriptome from uninfected stems, of AC18 with that of the highly susceptible wild olive clone AC15, GO-term enrichment analysis revealed terms related to systemic acquired resistance, plant cell wall biogenesis and assembly, and phenylpropanoid and lignin metabolism. qRT-PCR analysis of phenylpropanoid and lignin metabolism-related genes showed differences in their expression between the two wild olive clones. Phenolic content of stem cell walls was higher in the resistant AC18. The total lignin content was similar in resistant and susceptible clones, but they differed in monolignol composition. Results from this work identifies putative key genes in wild olive that could aid in breeding olive cultivars resistant, to D. V. dahliae. The research highlights the constitutive defence mechanisms that are effective in protecting against pathogens and our findings may contribute to the deciphering the molecular basis of VW resistance in olive and the conservation and utilization of wild olive genetic resources to tackle future agricultural challenges towards.

Indexed as

Disease ResistanceLigninOleaPlant DiseasesTranscriptomeVerticilliumAscomycotaGene Expression ProfilingGene Expression Regulation, PlantLigninDefoliating pathotypeLignin metabolismOlea europaeaRootstockVerticillium dahliaeVerticillium wiltWild olive

Identifiers

PMID40045216
PMCPMC11884133

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.