Evidence map›Paper›PMID 40045116›Full record

ArticleWorld journal of microbiology & biotechnology2025

Characterization of a Na

Qianli Huang, Chunhua Zhu, Tao Hong, Hebin Li, Lijun Li, Mingjing Zheng, Zhipeng Li, Zedong Jiang, Hui Ni, Yanbing Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qianli HuangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Chunhua ZhuCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Tao HongCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Hebin LiDepartment of Pharmacy, Xiamen Medical College, Xiamen, 361008, China.
Lijun LiCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Mingjing ZhengCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Zhipeng LiCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Zedong JiangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Hui NiCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China.
Yanbing ZhuCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, 361021, China. yanbingzhu@jmu.edu.cn.

Funding

National Natural Science Foundation of China 22178142the Fujian Provincial Department of Science and Technology 2024Y4008the Natural Science Foundation of Fujian Province of China 2023J011652
6 · The paper itself

Abstract

Hyaluronic acid (HA) is a natural polymer that can be degraded by hyaluronate lyase into oligomers with diverse biological activities. In this study, a novel hyaluronate lyase (named HCLase6) of polysaccharide lyase family 6 from Microbulbifer sp. ALW1 was cloned and characterized. Optimal temperature and pH for HCLase6 was determined to be 40 ℃ and 5.0, respectively. It displayed good stability at temperature up to 45 ℃ and in the pH range of 4.0-9.0. In addition, HCLase6 demonstrated good tolerance to detergents of Tween 20, Tween 80 and SDS, and was halophilic and halotolerant to Na

Indexed as

AlteromonadaceaeAntioxidantsPolysaccharide-LyasesSodiumBacterial ProteinsCloning, MolecularEnzyme StabilityHumansHyaluronic AcidHydrogen-Ion ConcentrationHydrolysisKeratinocytesMolecular Dynamics SimulationTemperatureAntioxidantsBacterial Proteinshyaluronate lyaseHyaluronic AcidPolysaccharide-LyasesSodiumHalo-stabilityHyaluronate lyaseMicrobulbifer Sp.Oligosaccharides

Identifiers

PMID40045116

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.