Evidence map›Paper›PMID 40045062›Full record

ArticleInternational ophthalmology2025

Choroidal vascularity ındex findings ın patients recovered from mild course COVID-19 pneumonia.

Muge Toprak, Enes Kesim, Buğra Karasu, Ali Riza Cenk Celebi

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Muge ToprakKocaeli City Hospital, Evliya Celebi Mh. Ertas Sk. Cornercity B Block No:12, 34944, Tuzla, Istanbul, Kocaeli, Turkey. mgtoprak@hotmail.com.ORCID http://orcid.org/0000-0002-0567-8449
Enes KesimDepartment of Ophthalmology, Okan University Medical School, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0083-975X
Buğra KarasuDepartment of Ophthalmology, Tuzla State Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-7362-4453
Ali Riza Cenk CelebiDepartment of Ophthalmology, Acibadem University Medical School, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7952-1241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the choroidal vascularity index (CVI) in individuals who have recovered from moderate pneumonia caused by COVID-19, using enhanced depth imaging optical coherence tomography (EDI-OCT).

methodsThis study included 43 patients who had recovered from SARS-CoV-2 infection with mild pneumonia (Group 1-COVID group), as well as 45 healthy individuals (Group 2- healthy control group). The study comprised COVID-19 patients who fully recovered from COVID-19 pneumonia. These patients were assessed 6 months after their pneumonia had totally resolved. The measurements were acquired via EDI-OCT investigations of the choroidal structures. The primary measure of interest was the CVI, which is defined as the ratio of the luminal area (LA) to the total choroidal area (TCA).

resultsPatients from Group 1 (COVID group) who had totally recovered exhibited significantly higher mean TCA, stromal area (SA), and LA compared to patients from Group 2 (control or healthy group). The two groups did not show a significant difference in CVI (p = 0.080).

conclusionChoroidal vascularity index can reveal the choroidal vascular physiology in patients who have fully recovered from COVID-19 pneumonia. EDI-OCT can be utilized to evaluate choroidal vascular alterations, serving as a non-invasive indicator for early vascular impairment following SARS-CoV-2 infection.

Indexed as

ChoroidCOVID-19SARS-CoV-2AdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedTomography, Optical CoherenceChoroidal vascular indexCovid-19Luminal areaTotal choroidal area

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.