Evidence map›Paper›PMID 40045038›Full record

ArticleNature reviews. Gastroenterology & hepatology2025

Developing an adaptive platform trial for evaluation of medical treatments for Crohn's disease.

Nurulamin M Noor, Shellie J Radford, Babak Choodari-Oskooei, Morris Gordon, Ailsa L Hart, Trish Hepburn, Ed Juszczak, James O Lindsay, Nicholas A Kennedy, Mahesh K B Parmar and 2 more

Abstract read
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In one paragraph

Article in Nature reviews. Gastroenterology & hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nurulamin M NoorDepartment of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID http://orcid.org/0000-0003-3426-6408
Shellie J RadfordNational Institute of Health Research Nottingham Biomedical Research Centre, University of Nottingham and Nottingham University Hospitals, Nottingham, UK.
Babak Choodari-OskooeiMRC CTU at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.
Morris GordonUniversity of Central Lancashire, Preston, UK.
Ailsa L HartSt Marks Hospital, Harrow, UK.
Trish HepburnNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK.
Ed JuszczakNottingham Clinical Trials Unit, School of Medicine, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0001-5500-2247
James O LindsayDepartment of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, UK.ORCID http://orcid.org/0000-0003-3353-9590
Nicholas A KennedyDepartment of Gastroenterology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
Mahesh K B ParmarMRC CTU at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.
Vipul JairathDivision of Gastroenterology, Department of Medicine, Western University, London, Ontario, Canada.
Gordon W MoranNational Institute of Health Research Nottingham Biomedical Research Centre, University of Nottingham and Nottingham University Hospitals, Nottingham, UK. Gordon.Moran@nottingham.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40045038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.