Evidence map›Paper›PMID 40044903›Full record

ArticleCommunications biology2025

Dynamic and intricate regulation by the Csr sRNAs in the Arctic Pseudoalteromonas fuliginea.

Zedong Duan, Li Liao, Tingyi Lai, Ruyi Yang, Jin Zhang, Bo Chen

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development of a CRISPR/Cas9-induced gene editing system forApplied and environmental microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zedong DuanKey Laboratory of Polar Ecosystem and Climate Change, Ministry of Education; Shanghai Key Laboratory of Polar Life and Environment Sciences; and School of Oceanography, Shanghai Jiao Tong University, Shanghai, China.ORCID http://orcid.org/0009-0002-0827-7605
Li LiaoKey Laboratory of Polar Ecosystem and Climate Change, Ministry of Education; Shanghai Key Laboratory of Polar Life and Environment Sciences; and School of Oceanography, Shanghai Jiao Tong University, Shanghai, China. liaoli@pric.org.cn.ORCID http://orcid.org/0000-0002-8548-1928
Tingyi LaiKey Laboratory of Polar Ecosystem and Climate Change, Ministry of Education; Shanghai Key Laboratory of Polar Life and Environment Sciences; and School of Oceanography, Shanghai Jiao Tong University, Shanghai, China.
Ruyi YangKey Laboratory for Polar Science, Ministry of Natural Resources, Polar Research Institute of China, Shanghai, China.
Jin ZhangKey Laboratory for Polar Science, Ministry of Natural Resources, Polar Research Institute of China, Shanghai, China.
Bo ChenKey Laboratory for Polar Science, Ministry of Natural Resources, Polar Research Institute of China, Shanghai, China.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 41976224National Natural Science Foundation of China (National Science Foundation of China) 42476264
6 · The paper itself

Abstract

The Csr (Carbon Storage Regulator) system is pivotal in controlling various cellular functions in most bacteria, primarily through the CsrA protein and its antagonistic sRNAs. However, riboregulatory networks are less explored in non-model organisms, particularly those in extreme environments. In this study, we discovered two new sRNAs of the Csr system, Pf2 and Pf3, in the Arctic bacterium Pseudoalteromonas fuliginea BSW20308, along with the previously known Pf1. By studying the impact of these Pf sRNAs on CsrA targetomes and physiological processes, we found a significant influence on various cellular functions and a collective effect on the interaction dynamics between CsrA and RNAs. Furthermore, we identified additional sRNAs that can interact with CsrA and mRNAs. Overall, our results emphasize the growing influence of the Csr system on cellular physiology through intricate sRNA regulation of CsrA, revealing riboregulatory network complexity and significance in non-model organisms.

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialPseudoalteromonasRNA, BacterialRNA-Binding ProteinsRNA, Small UntranslatedArctic RegionsRNA, MessengerBacterial ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerRNA, Small Untranslated

Identifiers

PMID40044903
PMCPMC11882849

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.